Functional assessments in the rodent stroke model.

Experimental & Translational Stroke Medicine
Krystal L SchaarSean I Savitz

Abstract

Stroke is a common cause of permanent disability accompanied by devastating impairments for which there is a pressing need for effective treatment. Motor, sensory and cognitive deficits are common following stroke, yet treatment is limited. Along with histological measures, functional outcome in animal models has provided valuable insight to the biological basis and potential rehabilitation efforts of experimental stroke. Developing and using tests that have the ability to identify behavioral deficits is essential to expanding the development of translational therapies. The present aim of this paper is to review many of the current behavioral tests that assess functional outcome after stoke in rodent models. While there is no perfect test, there are many assessments that are sensitive to detecting the array of impairments, from global to modality specific, after stroke.

References

Mar 15, 1992·Behavioural Brain Research·I Q WhishawB P Gorny
Mar 20, 1992·Brain Research·C G MarkgrafN Schneiderman
Aug 1, 1991·Stroke; a Journal of Cerebral Circulation·T X GionetJ R West
Feb 1, 1991·Journal of Neuroscience Methods·C P MontoyaS B Dunnett
Jun 18, 1990·Behavioural Brain Research·T M BarthT Schallert
Jul 1, 1988·Journal of Neurosurgery·W G ObanaM C Nishimura
May 1, 1986·Stroke; a Journal of Cerebral Circulation·J B BedersonH Bartkowski
Apr 1, 1968·The Journal of Pharmacy and Pharmacology·B J Jones, D J Roberts
May 1, 1984·Journal of Neuroscience Methods·R Morris
May 1, 1984·Stroke; a Journal of Cerebral Circulation·B T VolpeH P Davis
Nov 1, 1995·Stroke; a Journal of Cerebral Circulation·R P StroemerC E Hulsebosch
Jun 1, 1993·Stroke; a Journal of Cerebral Circulation·M GrabowskiB B Johansson
Sep 1, 1996·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·F YonemoriA Tamura
Nov 20, 1998·Behavioural Brain Research·G A MetzH van de Meent
Mar 29, 2001·Brain Research Bulletin·A L BairdS B Dunnett
Jul 9, 2002·Journal of Neuroscience Methods·Li ZhangMichael Chopp
Oct 5, 2002·Stroke; a Journal of Cerebral Circulation·Ya HuaGuohua Xi
Mar 1, 1957·Journal of the American Pharmaceutical Association·N W DUNHAM, T S MIYA
Mar 23, 2004·Behavioural Brain Research·J Leigh Leasure, Timothy Schallert
Jul 9, 2004·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Claire L Gibson, Sean P Murphy
Jan 29, 2005·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Jieli ChenMichael Chopp
Jun 1, 2005·Behavioural Brain Research·Gerlinde A MetzOtto W Witte
Nov 3, 2005·Journal of Experimental Psychology. Human Perception and Performance·Jason Tipples
Apr 20, 2006·Journal of Neuroscience Methods·Se Hoon ChoiTimothy Schallert
Oct 3, 2006·NeuroRx : the Journal of the American Society for Experimental NeuroTherapeutics·Timothy Schallert
Oct 28, 2006·Experimental Neurology·Valentine BouëtPascale Schumann-Bard
Dec 7, 2007·Experimental Neurology·Rachel P Allred, Theresa A Jones
Mar 8, 2008·Journal of Neuroscience Methods·Rachel P AllredTheresa A Jones
Aug 16, 2008·The European Journal of Neuroscience·Mariam Alaverdashvili, Ian Q Whishaw
Apr 23, 2009·Journal of Neuroscience Methods·Kelly A Tennant, Theresa A Jones

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Citations

Jun 22, 2012·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Kenmei MizutaniKin-Ya Kubo
Jan 25, 2013·Experimental & Translational Stroke Medicine·Jessica M Livingston-Thomas, R Andrew Tasker
Oct 31, 2012·International Journal of Molecular Sciences·Jens MinnerupChristoph Kleinschnitz
Jun 25, 2013·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Kenmei MizutaniKan Shimpo
Aug 28, 2014·CNS Drugs·Kiyoshi KikuchiSalunya Tancharoen
Sep 2, 2014·Neuroscience Research·Bárbara Paula Coelho, Arthur Giraldi-Guimarães
Jun 1, 2011·Cellular and Molecular Life Sciences : CMLS·Anu Lipsanen, Jukka Jolkkonen
Apr 27, 2011·Expert Review of Cardiovascular Therapy·Douglas James Cook, Michael Tymianski
Aug 19, 2015·Journal of Basic and Clinical Physiology and Pharmacology·Sruthi Ramagiri, Rajeev Taliyan
Feb 5, 2015·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Francesco BlasiCenk Ayata
Mar 5, 2015·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Andrés da Silva-CandalFrancisco Campos
Oct 20, 2015·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Maryam HadadhaAhmad Reza Bandegi
Oct 16, 2015·Behavioral and Brain Functions : BBF·Danielle N DollJames W Simpkins
Mar 29, 2016·Translational Stroke Research·Thomas A Kent, Pitchaiah Mandava
Sep 28, 2015·Behavioral and Brain Functions : BBF·Yuan YangJingjing Li
Dec 19, 2015·Evidence-based Complementary and Alternative Medicine : ECAM·Xumei WangLu Chen
Sep 15, 2015·Journal of Neuroscience Methods·Nitish MittalTimothy Schallert
Apr 20, 2016·Frontiers in Cellular Neuroscience·Stefanie SeilerHans Rudolf Widmer
Oct 22, 2013·Journal of Neuroscience Methods·Albert M I Barth, Istvan Mody
Nov 10, 2013·Behavioural Brain Research·Vincent PerticiPatrick Decherchi
Jan 7, 2014·Behavioural Brain Research·Monika Liguz-LecznarMalgorzata Kossut
Mar 28, 2013·Stroke Research and Treatment·Saara ParkkinenJukka Jolkkonen
May 14, 2014·Behavioural Brain Research·Sylvie GirardStuart M Allan

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