PMID: 16613583Apr 15, 2006Paper

Functional chemokine receptors in allergic diseases: is CCR8 a novel therapeutic target?

Mini Reviews in Medicinal Chemistry
E MitsuyamaO Kaminuma

Abstract

CC chemokine receptor (CCR) 8, which is expressed on Th2 cells and eosinophils, has been implicated in allergic diseases. This review represents an overview of the functional roles of CCR8 in the pathogenesis of eosinophilic inflammation and debates the potential of recently developed CCR8 antagonists to treat allergic disorders.

Citations

Jan 20, 2011·Nature Immunology·Gudrun F Debes, Malissa C Diehl
Oct 27, 2009·Organic Letters·Trine P PetersenTrond Ulven

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