Functional Coordination of the Chromatin-Remodeling Factor AtINO80 and the Histone Chaperones NRP1/2 in Inflorescence Meristem and Root Apical Meristem

Frontiers in Plant Science
Huijia KangYan Zhu

Abstract

Chromatin structure requires proper modulation in face of transcriptional reprogramming in the context of organism growth and development. Chromatin-remodeling factors and histone chaperones are considered to intrinsically possess abilities to remodel chromatin structure in single or in combination. Our previous study revealed the functional synergy between the Arabidopsis chromatin-remodeling factor INOSITOL AUXOTROPHY 80 (AtINO80) and the histone chaperone NAP1-RELATED PROTEIN 1 (NRP1) and NRP2 in somatic homologous recombination, one crucial pathway involved in repairing DNA double strand breaks. Here, we report genetic interplay between AtINO80 and NRP1/2 in regulating inflorescence meristem (IM) and root apical meristem (RAM) activities. The triple mutant atino80-5 m56-1 depleting of both AtINO80 (atino80-5) and NRP1/2 (m56-1) showed abnormal positioning pattern of floral primordia and enlargement of IM size. Higher mRNA levels of several genes involved in auxin pathway (e.g., PIN1, FIL) were found in the inflorescences of the triple mutant but barely in those of the single mutant atino80-5 or the double mutant m56-1. In particular, the depletion of AtINO80 and NRP1/2 decreased histone H3 levels within the chromatin region...Continue Reading

References

Apr 13, 2000·The Plant Cell·D ReinhardtC Kuhlemeier
Feb 6, 2003·Genes & Development·Sabrina SabatiniBen Scheres
Nov 25, 2003·Nature·Didier ReinhardtCris Kuhlemeier
Jan 21, 2006·Science·Jian XuBen Scheres
Jan 16, 2007·The Plant Journal : for Cell and Molecular Biology·Carol L WenzelJim Mattsson
Aug 8, 2008·Plant Physiology·Mathias SchuetzJim Mattsson
Apr 10, 2009·Annual Review of Biochemistry·Cedric R Clapier, Bradley R Cairns
Nov 26, 2009·Proceedings of the National Academy of Sciences of the United States of America·Nick Fulcher, Robert Sablowski
Jun 26, 2010·Nature·Zhong ZhaoJan U Lohmann
May 27, 2011·Proceedings of the National Academy of Sciences of the United States of America·Sumiko AdachiMasaaki Umeda
Sep 6, 2013·Current Opinion in Plant Biology·Wendy Ann Peer
Apr 24, 2014·Nature Reviews. Molecular Cell Biology·Renze Heidstra, Sabrina Sabatini
Aug 5, 2014·Trends in Cell Biology·Christian B Gerhold, Susan M Gasser
Jan 22, 2015·The Plant Cell·Maciek Adamowski, Jiří Friml
Mar 18, 2015·The Plant Journal : for Cell and Molecular Biology·Wangbin ZhouWen-Hui Shen
Apr 3, 2015·The Plant Journal : for Cell and Molecular Biology·Chi ZhangAiwu Dong
Oct 7, 2015·Trends in Plant Science·Xiangpei KongZhaojun Ding
May 21, 2016·Wiley Interdisciplinary Reviews. Developmental Biology·Carlos S Galvan-AmpudiaTeva Vernoux
Jun 29, 2017·Genome Biology·V K Chaithanya PonnaluriSriharsa Pradhan
Oct 11, 2017·Journal of Experimental Botany·Ying Wang, Yuling Jiao
Apr 21, 2018·The Plant Journal : for Cell and Molecular Biology·Jing MaWen-Hui Shen
Sep 7, 2018·Frontiers in Plant Science·Simon P OjoloYuan Qin

❮ Previous
Next ❯

Citations

Oct 31, 2019·FEBS Letters·Katiuska González-ArzolaMiguel Á De la Rosa
Sep 20, 2019·International Journal of Molecular Sciences·Jianhao WangSongguang Yang
Oct 23, 2019·Biomolecules·Eduardo Mateo-BonmatíKarin Ljung
Nov 19, 2020·Journal of Experimental Botany·Paula Casati, Maria Sol Gomez
May 4, 2021·FEBS Open Bio·Katiuska González-ArzolaMiguel A De la Rosa
Nov 9, 2021·Bioengineered·Suraj PatilVinay Kumar

❮ Previous
Next ❯

Methods Mentioned

BETA
Immuno-Precipitation
Scanning electron microscopy
electron microscopy
ChIP
transgenic
affinity

Software Mentioned

INTACT

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.