Functional correlates of lower cognitive test scores in essential tremor.

Movement Disorders : Official Journal of the Movement Disorder Society
Elan D Louis

Abstract

Although motor features have been the defining element of essential tremor (ET), lower neurocognitive test scores are increasingly being recognized. However, the clinical correlates, if any, of these lower test scores remain largely unexplored. The aim of this study was to determine whether cognitive test scores in ET have any functional correlates. The Modified Mini Mental Status Examination (MMSE), Katz Activities of Daily Living (ADL) scale and Lawton Instrumental (I) ADL scale were administered to 95 cases. The Katz ADL score (rho = 0.26, P = 0.01) and Lawton IADL score (rho = 0.32, P = 0.001) were correlated with MMSE scores, such that poorer cognitive performance indicated greater dysfunction. Furthermore, cognitive test scores were a better predictor of functional disability than was tremor severity. Poorer cognitive performance in ET was associated with greater functional deficit. Cognition should enter the clinical dialog with ET patients as an issue of clinical significance.

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Citations

Apr 14, 2011·Nature Reviews. Neurology·Félix Bermejo-Pareja
Apr 29, 2014·Archives of Physical Medicine and Rehabilitation·Ashwini K RaoElan D Louis
May 14, 2014·Progress in Neurobiology·Jean-François SchmouthGuy A Rouleau
Apr 14, 2011·Parkinsonism & Related Disorders·Elan D Louis, Michael S Okun
Mar 2, 2013·Movement Disorders : Official Journal of the Movement Disorder Society·Maira Tonidandel BarbosaFrancisco Cardoso
Apr 24, 2014·Movement Disorders : Official Journal of the Movement Disorder Society·Mark Walterfang, Bart P van de Warrenburg
Jan 6, 2012·Parkinsonism & Related Disorders·Vijay Chandran, Pramod Kumar Pal
Feb 2, 2013·Gait & Posture·Ashwini K RaoElan D Louis
May 25, 2013·Neurocase·S Lee HongElizabeth B Torres
Nov 15, 2013·Therapeutic Advances in Neurological Disorders·Sarah C JanickiElan D Louis
Aug 29, 2012·Journal of Neural Transmission·S YerramI Bodis-Wollner
Jul 19, 2014·Alzheimer Disease and Associated Disorders·In-Seok ParkJoong-Seok Kim
Oct 5, 2019·Journal of the International Neuropsychological Society : JINS·Tess E K CersonskyStephanie Cosentino
May 5, 2017·Frontiers in Neurology·Elan D LouisStephanie Cosentino
Oct 12, 2018·Journal of the International Neuropsychological Society : JINS·Tess E K CersonskyStephanie Cosentino

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