Functional electrical stimulation effect on skeletal muscle blood flow measured with H2(15)O positron emission tomography

Archives of Physical Medicine and Rehabilitation
Oscar U ScreminMark Mandelkern

Abstract

To test the hypothesis that the limitation in muscle power development with functional electrical stimulation (FES) results from an insufficient increase in muscle blood flow (MBF) in response to activity. Five subjects with neurologically complete spinal cord injury (SCI) were tested to measure the MBF response to FES-induced knee extension. The MBF response to voluntary knee extension was measured in five age-matched, able-bodied controls. MBF was measured with positron emission tomography (PET) using H2(15)O as a tracer. Three scans were performed with muscle at rest (baseline), immediately after 16min of FES-induced or voluntary knee extension (activity), and 20min after the second scan (recovery). In SCI subjects, mean +/-SE MBF (mL/100g/min) values were: baseline = 1.85 +/- .48; post-FES = 31.9 +/- 5.65 (p = .0058 vs baseline); recovery = 6.06 +/- 1.52 (p = .0027 vs baseline). In able-bodied controls, mean +/-SE MBF values were: baseline = 8.52 +/- 3.24, post-voluntary exercise = 12.62 +/- 3.03 (p = .023 vs post-FES in SCI subjects); recovery = 10.7 +/- 6.01. MBF does not appear to be the limiting factor in muscle power generation with FES. The greater increase in MBF observed with FES in SCI subjects when compared with a...Continue Reading

References

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Citations

Jul 26, 2003·Archives of Physical Medicine and Rehabilitation·Thomas W Janssen, Maria T Hopman
Oct 31, 2002·The Journal of Orthopaedic and Sports Physical Therapy·Gregory F MartelChristopher G Roseboom
Oct 27, 2009·PM & R : the Journal of Injury, Function, and Rehabilitation·Stephen F FigoniBabak Cohen
Dec 22, 1999·Archives of Physical Medicine and Rehabilitation·A M ScreminO U Scremin
Apr 20, 2018·American Journal of Physical Medicine & Rehabilitation·Thomas J BartonDick H J Thijssen
Apr 2, 2010·American Journal of Physical Medicine & Rehabilitation·Oscar U ScreminMark Mandelkern
May 6, 2016·American Journal of Physical Medicine & Rehabilitation·Christof A J SmitThomas W J Janssen
May 26, 2021·Neuromodulation : Journal of the International Neuromodulation Society·Julio Cesar FurlanMilos Radomir Popovic
Mar 7, 2014·Journal of Neuroengineering and Rehabilitation·Sung Ho JangSang Seok Yeo

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