PMID: 6398609Jan 1, 1984Paper

Functional eustachian tube obstruction and otitis media in a primate model. A review

Acta Oto-laryngologica. Supplementum
W J Doyle

Abstract

In most infants and children with chronic otitis media with effusion, an inability to dilate the Eustachian tube actively has been documented. This functional tubal obstruction has been suggested to underlie the development of the disease. To test this possibility a variety of models using the Rhesus monkey were developed. The normal tubal dilatory system was impaired, resulting in sterile otitis media with effusion. The duration and nature of the disease was shown to be dependent on the severity and duration of the impairment in tubal function. These studies support the causative role of functional Eustachian tube obstruction in the development of otitis media with effusion and provide a series of models in which to study the etiology, pathogenesis, sequelae and complications as well as the treatment and preventions of the pathology in an animal species physiologically and anatomically similar to man.

References

Jul 1, 1977·The Annals of Otology, Rhinology & Laryngology. Supplement·E I CantekinD C Phillips
Aug 1, 1977·The Laryngoscope·C D Bluestone
Mar 1, 1976·The Annals of Otology, Rhinology, and Laryngology·E I CantekinL P Parkin
Mar 1, 1974·The Annals of Otology, Rhinology, and Laryngology·C D BluestoneW S Andrus
Jul 1, 1970·Archives of Otolaryngology·J D Rankin, C S Karmody
Aug 1, 1970·The Annals of Otology, Rhinology, and Laryngology·M M PaparellaY Kaneko
Feb 1, 1970·The Annals of Otology, Rhinology, and Laryngology·G O Proud, H Odoi
Aug 1, 1969·The Annals of Otology, Rhinology, and Laryngology·C E Reiner, J L Pulec
May 1, 1980·The Annals of Otology, Rhinology & Laryngology. Supplement·W J DoyleM I Siegel
May 1, 1980·The Annals of Otology, Rhinology & Laryngology. Supplement·E I CantekinK K Kimes
Mar 1, 1982·The Annals of Otology, Rhinology, and Laryngology·E I CantekinC D Bluestone
Jan 1, 1982·Acta Anatomica·M M SaadT R Gest
Dec 1, 1959·The Annals of Otology, Rhinology, and Laryngology·J SADEB H SENTURIA

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Citations

Dec 14, 2012·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·William J DoyleMargaretha L Casselbrant
Jun 1, 1995·The Laryngoscope·K E ScharfP J Gannon
Sep 14, 2007·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Tarik SapciEren Gozke
Jun 29, 2010·International Journal of Pediatric Otorhinolaryngology·William J Doyle, J Douglas Swarts
Apr 12, 2016·International Journal of Pediatric Otorhinolaryngology·Allison P GrembaMargaretha L Casselbrant
May 1, 1987·American Journal of Otolaryngology·Y Hanamure, D J Lim
Apr 1, 1994·International Journal of Pediatric Otorhinolaryngology·M NiemeläA Hannuksela
Feb 5, 2014·International Journal of Pediatric Otorhinolaryngology·Miriam S TeixeiraWilliam J Doyle
May 28, 2015·The Laryngoscope·Robert K JacklerNikolas H Blevins
Jul 26, 2007·Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society·Peter L Santa MariaReza Ghassemifar
Mar 16, 2017·The Journal of Laryngology and Otology·P M PicciottiE Scarano
Apr 1, 1989·The Annals of Otology, Rhinology & Laryngology. Supplement·M L CasselbrantK Honda
May 4, 2017·Computer Methods in Biomechanics and Biomedical Engineering·B AreiasR M Natal Jorge
Oct 28, 2017·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Junbo ZhangLei Zhang

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