Functional gastrointestinal disorders as a public health problem

Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society
N J Talley

Abstract

The functional gastrointestinal disorders (FGIDs) are a heterogeneous group of chronic conditions that are considered to be important to public health because they are remarkably common, can be disabling, and induce a major social and economic burden. Despite the Rome consensus process, the line defining true abnormality from health is as yet imprecise. Furthermore, the concept that the FGIDs have no pathological or biochemical correlates is starting to unravel, and some candidate morphometric abnormalities (e.g. duodenal eosinophilia, colonic mastocytosis) have been documented. The quality of care that patients with FGIDs receive is not well understood, despite the high volume of patients seen in primary and specialty care. There are a remarkable number of symptom-based and disease-based co-morbidities that appear to be more common in those with FGIDs that are not alone explained by coexistent somatization. Whether there is any means of preventing the development of FGIDs post-infection is untested but has vast public health implications. Defining disease severity remains key to better understanding the public health impact of FGIDs; severity is probably influenced by the intestinal and extra-intestinal symptom burden, psychol...Continue Reading

References

Jul 15, 1992·American Journal of Epidemiology·N J TalleyL J Melton
Jun 15, 1992·Annals of Internal Medicine·D A Drossman, W G Thompson
Dec 1, 1995·Gastroenterology·N J TalleyR W Evans
Jan 15, 1995·Annals of Internal Medicine·D M OwensN J Talley
Jan 19, 2000·The American Journal of Gastroenterology·N A KoloskiP M Boyce
Apr 12, 2000·Family Practice·M Dixon-Woods, S Critchley
Apr 24, 2001·The American Journal of Gastroenterology·N J TalleyR Poulton
Nov 28, 2001·The American Journal of Gastroenterology·R L LevyA D Feld
May 2, 2002·Gastroenterology·Robert S SandlerRobert Rubin
May 29, 2002·Alimentary Pharmacology & Therapeutics·H B El-SeragD Bjorkman
Jun 25, 2002·Journal of Clinical Gastroenterology·Rosalie P PatelBarbara J Zarowitz
Sep 21, 2002·Lancet·Nicholas J Talley, Robin Spiller
Mar 26, 2003·The American Journal of Gastroenterology·George F LongstrethJoshua J Ofman
Jul 23, 2003·The American Journal of Gastroenterology·Simon P DunlopRobin C Spiller
Aug 28, 2003·Alimentary Pharmacology & Therapeutics·H B El-Serag, N J Talley
Dec 4, 2003·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·Y A SaitoG R Locke
Mar 17, 2004·Alimentary Pharmacology & Therapeutics·H B El-Serag, N J Talley
Jun 10, 2004·Gastroenterology·George F Longstreth, Janis F Yao
Jan 19, 2005·The American Journal of Gastroenterology·G Richard LockeNicholas J Talley
Jan 27, 2005·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·G R LockeN J Talley
May 3, 2005·Gastroenterology Clinics of North America·Filippo Cremonini, Nicholas J Talley
May 20, 2005·American Journal of Obstetrics and Gynecology·Muriel K BorehamJoseph I Schaffer
Oct 20, 2005·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Anthony LemboDouglas A Drossman
Nov 8, 2005·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Yuri A SaitoNicholas J Talley
Dec 3, 2005·BMC Neurology·James N BaraniukSonja Hess S
Dec 6, 2005·American Journal of Obstetrics and Gynecology·John E JelovsekMark D Walters
Feb 1, 2006·PharmacoEconomics·Stefanie Maxion-BergemannRito Bergemann
Mar 24, 2006·American Journal of Epidemiology·Pertti AroLars Agréus
May 9, 2006·Gastroenterology·George F LongstrethRobin C Spiller
Jul 20, 2006·The American Journal of Gastroenterology·Nicholas J ShaheenRobert S Sandler
Aug 8, 2006·Gastroenterology·John K MarshallUNKNOWN Walkerton Health Study Investigators
Sep 8, 2006·European Journal of Gastroenterology & Hepatology·Natasha A KoloskiNicholas J Talley
Jan 5, 2007·Journal of Gastroenterology and Hepatology·Full-Young Chang, Ching-Liang Lu
Jan 24, 2007·Gastroenterology·Giovanni BarbaraRoberto Corinaldesi
Mar 21, 2007·Lancet·Peter HenningsenWolfgang Herzog
Mar 27, 2007·Gastroenterology·Tobias LiebregtsGerald Holtmann
Apr 21, 2007·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Ana RuigómezJulián Panés

❮ Previous
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Citations

Oct 20, 2010·International Journal of Colorectal Disease·Hamid Mohaghegh ShalmaniMohammad Reza Zali
Sep 29, 2011·Irish Journal of Medical Science·K WalshE M Quigley
Jul 21, 2009·Current Gastroenterology Reports·Yvette TachéAndreas Stengel
Aug 13, 2011·The New England Journal of Medicine·Anthony J LemboJeffrey M Johnston
Apr 2, 2011·Journal of Gastroenterology and Hepatology·Full-Young Chang, Ching-Liang Lu
Oct 1, 2010·Experimental Biology and Medicine·Andreas Stengel, Yvette Taché
Mar 4, 2011·Journal of Neurogastroenterology and Motility·Govind K MakhariaAnand Krishnan
May 24, 2011·Journal of Neurogastroenterology and Motility·Hidekazu SuzukiToshifumi Hibi
Oct 10, 2013·Evidence-based Complementary and Alternative Medicine : ECAM·Zhi YuBin Xu
Jul 12, 2013·Gastroenterology Research and Practice·Marco D GulewitschAngelika A Schlarb
Jun 11, 2014·Nature Reviews. Gastroenterology & Hepatology·Yasser Al Omran, Qasim Aziz
Jan 5, 2010·Gastroenterology·Anthony J LemboJeffrey M Johnston
Oct 30, 2010·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Qiqi ZhouG Nicholas Verne
Jun 25, 2014·Expert Opinion on Investigational Drugs·Shilan MozaffariMohammad Abdollahi
Feb 11, 2016·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·H L ParkerM R Fox
Jun 23, 2009·Journal of the Chinese Medical Association : JCMA·Full-Young Chang, Ching-Liang Lu
Dec 6, 2011·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·Linda Bjork OlafsdottirBjarni Thjodleifsson
Aug 23, 2011·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Spencer D DornDouglas A Drossman
May 17, 2011·European Journal of Internal Medicine·Branka F FilipovićBranislav R Filipović
Aug 12, 2009·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·E Rey, N J Talley
Oct 28, 2015·Gastroenterology·Jan Tack, Arnold Wald
Jun 11, 2015·Journal of Travel Medicine·Brian L PikeChad K Porter
Sep 8, 2015·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Jan Tack, Maura Corsetti
Aug 26, 2015·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·H PaulaN J Talley
Jul 1, 2009·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·H SuzukiT Hibi
Jun 2, 2012·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·S ElsenbruchS Benson
May 29, 2013·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·M BouchouchaR Benamouzig
Jul 25, 2012·Annals of the New York Academy of Sciences·Sven BensonSigrid Elsenbruch
Sep 3, 2013·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·H VanheelJ Tack
Jan 31, 2013·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·R S ChoungN J Talley
Jun 4, 2013·Alimentary Pharmacology & Therapeutics·B E LacyN J Talley
Oct 21, 2009·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·N ZarateQ Aziz
Mar 5, 2016·Acta Paediatrica·Peter L LuCarlos A Velasco-Benítez
May 9, 2015·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·A B VegaM Barenys
Mar 3, 2015·Alimentary Pharmacology & Therapeutics·D Le PluartC Julia
Jul 24, 2015·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·N A KoloskiN J Talley
Jan 25, 2014·Evidence-based Complementary and Alternative Medicine : ECAM·Siyuan ZhouYing Li
Apr 7, 2015·Digestive Diseases and Sciences·Michael D CrowellNicholas J Talley
Jun 17, 2015·The American Journal of Gastroenterology·Carla CirilloPieter Vanden Berghe
Sep 24, 2014·Psychotherapy Research : Journal of the Society for Psychotherapy Research·Antonina A Mikocka-WalusJane M Andrews

❮ Previous
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