Functional genomics of Buchnera and the ecology of aphid hosts

Molecular Ecology
Nancy A Moran, Patrick H Degnan

Abstract

In many animal groups, mutualistic bacterial symbionts play a central role in host ecology, by provisioning rare nutrients and thus enabling specialization on restricted diets. Among such symbionts, genomic studies are most advanced for Buchnera, the obligate symbiont of aphids, which feed on phloem sap. The contents of the highly reduced Buchnera genomes have verified its role in aphid nutrition. Comparisons of Buchnera gene sets indicate ongoing, irreversible gene losses that are expected to affect aphid nutritional needs. Furthermore, almost all regulatory genes have been eliminated, raising the question of whether and how gene expression responds to environmental change. Microarray studies on genome-wide expression indicate that Buchnera has evolved some constitutive changes in gene expression: homologues of heat stress genes have elevated transcript levels in Buchnera (relative to other bacteria) even in the absence of stress. Additionally, the microarray results indicate that responses to heat stress and to amino acid availability are both few and modest. Observed responses are consistent with control by the few ancestral regulators retained in the genome. Initial studies on the role of host genes in mediating the symbios...Continue Reading

References

Apr 26, 1994·Proceedings of the National Academy of Sciences of the United States of America·C Y LaiP Baumann
Apr 2, 1996·Proceedings of the National Academy of Sciences of the United States of America·N A Moran
Dec 9, 1998·Nature·S L Rutherford, S Lindquist
May 6, 1999·Journal of Molecular Evolution·K Komaki, H Ishikawa
Jun 12, 2001·Molecular Phylogenetics and Evolution·J J WernegreenN A Moran
Oct 5, 2001·Trends in Genetics : TIG·A MiraN A Moran
May 25, 2002·Nature·Mario A FaresEladio Barrio
Jun 29, 2002·Science·Ivica TamasSiv G E Andersson
Sep 6, 2002·Proceedings of the National Academy of Sciences of the United States of America·Colin DaleNancy A Moran
Oct 19, 2002·Proceedings of the National Academy of Sciences of the United States of America·Natsuko KondoTakema Fukatsu
Jan 11, 2003·Proceedings of the National Academy of Sciences of the United States of America·Roeland C H J van HamAndrés Moya
Feb 4, 2003·Proceedings of the National Academy of Sciences of the United States of America·Kerry M OliverMartha S Hunter
Jun 7, 2003·Molecular Microbiology·Jennifer L WilcoxNancy A Moran
Jul 16, 2003·Proceedings of the National Academy of Sciences of the United States of America·William Martin
Jul 30, 2003·Proceedings of the National Academy of Sciences of the United States of America·Rosario GilAndrés Moya
Oct 7, 2003·Proceedings of the National Academy of Sciences of the United States of America·Nancy A MoranJennifer L Wilcox
Oct 14, 2003·PLoS Biology·Christian BraendleDavid L Stern
Apr 20, 2004·Journal of Bacteriology·Beatriz Sabater-MuñozAmparo Latorre
Nov 9, 2004·Current Opinion in Genetics & Development·Nancy A Moran, Gordon R Plague
Dec 14, 2004·Microbiology and Molecular Biology Reviews : MMBR·Evelyn ZientzRoy Gross
Mar 1, 2005·Trends in Parasitology·Serap AksoyMichael J Lehane
Apr 1, 2005·PLoS Biology·Emmanuelle LeratNancy A Moran
Apr 1, 2005·Proceedings of the National Academy of Sciences of the United States of America·Atsushi NakabachiTakema Fukatsu
Jun 2, 2005·Evolution; International Journal of Organic Evolution·Michael A D GoodismanMichael A Wells
Oct 1, 2005·Proceedings of the National Academy of Sciences of the United States of America·Nancy A MoranHoward Ochman
Sep 1, 1994·Applied and Environmental Microbiology·L Baumann, P Baumann

❮ Previous
Next ❯

Citations

Mar 11, 2011·Cellular and Molecular Life Sciences : CMLS·Shuji Shigenobu, Alex C C Wilson
Sep 13, 2008·Proceedings of the National Academy of Sciences of the United States of America·Elhanan BorensteinEytan Ruppin
Apr 2, 2010·Proceedings. Biological Sciences·Wilfried KaiserDavid Giron
Oct 30, 2013·Proceedings of the National Academy of Sciences of the United States of America·Vittorio BoscaroGiulio Petroni
May 15, 2007·Proceedings of the National Academy of Sciences of the United States of America·Nancy A Moran
Feb 27, 2008·Evolution; International Journal of Organic Evolution·Eric M JansonPatrick Abbot
Nov 2, 2016·Proceedings of the National Academy of Sciences of the United States of America·Rebecca A Chong, Nancy A Moran
Apr 23, 2017·Genesis : the Journal of Genetics and Development·Rodrigo Nunes-da-FonsecaHelena Marcolla Araujo
May 25, 2010·Protoplasma·Emily L ClarkStephen F Hubbard
Jun 16, 2010·Molecular Microbiology·Susanne HaiderMatthias Horn
Apr 22, 2006·Molecular Ecology·Carol Eunmi Lee, Thomas Mitchell-Olds
Jun 20, 2014·Journal of Chemical Ecology·David Giron, Gaëlle Glevarec
Apr 17, 2019·Molecular Biology and Evolution·Rebecca A ChongNancy A Moran
Oct 25, 2013·Molecular Ecology·Adam J MartinezKerry M Oliver
Oct 27, 2015·G3 : Genes - Genomes - Genetics·Florence GutzwillerCasey M Bergman
Aug 16, 2018·Parasites & Vectors·Ephantus J MuturiChang-Hyun Kim
Oct 26, 2011·Journal of Evolutionary Biology·Julien MartinezJ Varaldi
Dec 6, 2020·Applied and Environmental Microbiology·Katherine M ElstonJeffrey E Barrick
Feb 7, 2016·Applied and Environmental Microbiology·Yuan-Chen ZhangXiang-Dong Liu

❮ Previous
Next ❯

Related Concepts

Related Feeds

African Trypanosomiasis

African trypanosomiasis, also known as sleeping sickness, is an insect-borne parasitic disease of humans and other animals. It is caused by protozoa of the species Trypanosoma brucei and almost invariably progresses to death unless treated. Discover the latest research on African trypanosomiasis here.