Treatment options for carcinoma of the cervix are guided by tumor stage, and include radical surgery, in cases where the tumor is confined to the cervix, or concurrent chemotherapy and radiotherapy. In those cases treated with chemoradiation, the ability to monitor the response to treatment in order to adapt the management plan during its course may be beneficial. This approach has the potential to offer an individualized treatment plan, allowing for differences in behavior between tumors to be addressed early, rather than a 'one size fits all' treatment approach. This article aims to review the use of evolving functional imaging techniques including diffusion-weighted MRI, dynamic contrast-enhanced MRI, and PET as tools for the evaluation of response to treatment of uterine cervical carcinoma.
Pelvic lesions in patients with treated cervical carcinoma: efficacy of pharmacokinetic analysis of dynamic MR images in distinguishing recurrent tumors from benign conditions
Early detection of treatment response by diffusion-weighted 1H-NMR spectroscopy in a murine tumour in vivo
Tumor perfusion studies using fast magnetic resonance imaging technique in advanced cervical cancer: a new noninvasive predictive assay
Differentiation between recurrent tumor and benign conditions after treatment of gynecologic pelvic carcinoma: value of dynamic contrast-enhanced subtraction MR imaging
Prediction of tumor control in patients with cervical cancer: analysis of combined volume and dynamic enhancement pattern by MR imaging
Quantitative dynamic contrast enhanced MRI of recurrent pelvic masses in patients treated for cancer
Estimating kinetic parameters from dynamic contrast-enhanced T(1)-weighted MRI of a diffusable tracer: standardized quantities and symbols
Contrast enhanced dynamic MRI of cervical carcinoma during radiotherapy: early prediction of tumour regression rate
Dynamic contrast-enhanced MR imaging of uterine cervical cancer: pharmacokinetic analysis with histopathologic correlation and its importance in predicting the outcome of radiation therapy
Reduced C-terminal Src kinase activity is correlated inversely with pp60(c-src) activity in colorectal carcinoma
Prognostic value of positron emission tomography using F-18-fluorodeoxyglucose in patients with cervical cancer undergoing radiotherapy
Posttherapy [18F] fluorodeoxyglucose positron emission tomography in carcinoma of the cervix: response and outcome
Apparent diffusion coefficient in cervical cancer of the uterus: comparison with the normal uterine cervix
Metabolic monitoring of advanced uterine cervical cancer neoadjuvant chemotherapy by using [F-18]-Fluorodeoxyglucose positron emission tomography: preliminary results in three patients
FDG-PET imaging for the assessment of physiologic volume response during radiotherapy in cervix cancer
The efficacy of FDG-PET in head-and-neck cancer with neck metastasis after definitive radiation treatment: in regard to Yao et al. (Int J Radiat Oncol Biol Phys 2005;63:991-999)
18F-fluoro-2-deoxy-D-glucose-positron emission tomography (PET)/PET-computed tomography in carcinoma of the cervix
Association of posttherapy positron emission tomography with tumor response and survival in cervical carcinoma
18-F-fluorodeoxyglucose-positron emission tomography evaluation of early metabolic response during radiation therapy for cervical cancer
Detection of lymph node metastasis in cervical and uterine cancers by diffusion-weighted magnetic resonance imaging at 3T
Diffusion-weighted magnetic resonance imaging in the early detection of response to chemoradiation in cervical cancer.
Semiquantitative and quantitative dynamic contrast-enhanced magnetic resonance imaging measurements predict radiation response in cervix cancer
Radiation dose is predictive of biochemical failure, local failure, and distant metastases. In regard to Kupelian et Al. (Int J Radiat Oncol Biol Phys 2008;71:16-22)
Toward a unified survival curve: in regard to Kavanagh and Newman (Int J Radiat Oncol Biol Phys 2008;71:958-959) and Park et al. (IntJ Radiat Oncol Biol Phys 2008;70:847-852)
Predicting control of primary tumor and survival by DCE MRI during early therapy in cervical cancer.
A combined pharmacokinetic and radiologic assessment of dynamic contrast-enhanced magnetic resonance imaging predicts response to chemoradiation in locally advanced cervical cancer.
Diffusion-weighted imaging in predicting and monitoring the response of uterine cervical cancer to combined chemoradiation
The role of dynamic contrast-enhanced and diffusion weighted magnetic resonance imaging in the female pelvis
Time-resolved vessel-selective digital subtraction MR angiography of the cerebral vasculature with arterial spin labeling.
Combined measurement of tumor perfusion and glucose metabolism for improved tumor characterization in advanced cervical carcinoma. A PET/CT pilot study using [15O]water and [18F]fluorodeoxyglucose
Time-window of early detection of response to concurrent chemoradiation in cervical cancer by using diffusion-weighted MR imaging: a pilot study
Predicting and Early Monitoring Treatment Efficiency of Cervical Cancer Under Concurrent Chemoradiotherapy by Intravoxel Incoherent Motion Magnetic Resonance Imaging
Carcinoma, Squamous Cell
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