Functional imaging of parotid glands: diffusion-weighted echo-planar MRI before and after stimulation

RöFo : Fortschritte auf dem Gebiete der Röntgenstrahlen und der Nuklearmedizin
C R HabermannG Adam

Abstract

To investigate the feasibility of diffusion-weighted (DW) echo-planar imaging (EPI) for measuring different functional conditions of the parotid gland and to compare different measurement approaches. Parotid glands of 27 healthy volunteers were examined with a DW EPI sequence (TR 1,500 msec, TE 77 msec, field-of-view 250 x 250 mm, pixel size 2.10 x 1.95 mm, section thickness 5 mm) before and after oral stimulation with commercially available lemon juice. The b factors used were 0, 500, and 1,000 sec/mm (2). Apparent diffusion coefficient (ADC) maps were digitally transferred to MRIcro (Chris Rorden, University of Nottingham, Great Britain) and evaluated with a manually placed circular region of interest (ROI) containing 100 - 200 pixel. Additional ROIs including the entire parotid gland were placed on either side. The results of both measurements were compared, using the Student's t test based on the median ADC values for each person. A two-tailed p-value of less than.05 was determined to indicate statistical significance. To compare both measurement approaches, the Pearson's correlation coefficient (r) was calculated. Diffusion-weighted echo-planar MR imaging successfully visualized the parotid glands of all volunteers. In a f...Continue Reading

Citations

Jan 9, 2007·European Radiology·Harriet C Thoeny, Frederik De Keyzer
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Mar 8, 2008·Journal of Neuroradiology. Journal De Neuroradiologie·Masayuki Maeda, Stephan E Maier
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