Abstract
Most prior research has focused on functional impairment as a consequence, rather than a predictor, of mood symptoms in bipolar disorder (BD). Yet the majority of this research has been cross-sectional, thus limiting conclusions regarding directionality of effects. Indeed, just as functional impairment may represent an important outcome of BD, it may also serve as a risk factor for future affective symptoms or episodes. Thus, the primary aim of this study was to evaluate functional impairment as a predictor of mood symptoms in BD. Ninety-two patients with bipolar I disorder, recruited from hospital settings, were administered the Modified Hamilton Rating Scale for Depression, Bech-Rafaelson Mania Scale, and UCLA Social Attainment Survey (SAS) at baseline and at four-month follow-up. Overall, patients evidenced a moderate level of functional impairment at both time points. Whereas baseline functional impairment was not associated with subsequent manic symptoms, baseline functional impairment was significantly predictive of depressive symptom levels at four-month follow-up. When individual SAS subscales were evaluated, impaired romantic relationship functioning and activity involvement were each significantly predictive of subseq...Continue Reading
References
Jun 1, 1978·Neuropharmacology·P BechT G Bolwig
Jan 1, 1978·Schizophrenia Bulletin·M J Goldstein
Aug 1, 1991·The British Journal of Psychiatry : the Journal of Mental Science·F BauwensJ Mendlewicz
Feb 10, 1988·Journal of Immunological Methods·B B Cohen
Feb 1, 1985·Psychiatry Research·I W MillerH Maddever
Nov 1, 1995·The American Journal of Psychiatry·M J GitlinC Hammen
May 1, 1993·The American Journal of Psychiatry·W CoryellG L Klerman
Jun 1, 1996·Acta Psychiatrica Scandinavica·G StefosJ Mendlewicz
Dec 28, 1999·Journal of Abnormal Psychology·M A Whisman
Mar 22, 2000·Psychiatry Research·K L SubotnikJ Ventura
Jun 1, 2000·The American Journal of Psychiatry·U FeskeD J Kupfer
Dec 2, 2000·Journal of Affective Disorders·A KusznirL T Young
Mar 29, 2001·Scandinavian Journal of Psychology·A K Torgalsbøen
Aug 21, 2001·Journal of Affective Disorders·M S BauerW O Williford
Jan 5, 2002·CNS Drugs·Per Bech
Jun 5, 2002·Archives of General Psychiatry·Lewis L JuddMartin B Keller
Oct 5, 2002·The Journal of Clinical Psychiatry·Lori L AltshulerMark A Frye
Apr 12, 2003·Bipolar Disorders·Elizabeth L GeorgeDawn O Taylor
Apr 29, 2003·The Journal of Clinical Psychiatry·Joseph R CalabreseKaren D Wagner
Jun 11, 2003·Journal of Consulting and Clinical Psychology·Margaret M ReaJim Mintz
Jun 26, 2003·The Journal of Clinical Psychiatry·Robert M PostWillem A Nolen
Aug 3, 2004·The American Journal of Psychiatry·Willem A NolenRobert M Post
Nov 24, 2004·The Journal of Clinical Psychiatry·Joseph R CalabreseMichael L Reed
Mar 15, 2005·Bipolar Disorders·Pilar SierraLuis Rojo
May 19, 2005·Bipolar Disorders·Andrea FagioliniEllen Frank
Jul 19, 2005·Psychiatry Research·David J MiklowitzGary S Sachs
Sep 1, 2005·Clinical Psychology Review·Sheri L Johnson
Oct 27, 2005·Journal of Affective Disorders·Joseph F Goldberg, Martin Harrow
May 25, 2006·Social Psychiatry and Psychiatric Epidemiology·F Curtis BreslinElizabeth Lin
Citations
Aug 11, 2011·Current Psychiatry Reports·David J Miklowitz
May 15, 2013·Lancet·John R Geddes, David J Miklowitz
Nov 26, 2014·BMC Psychiatry·Maria Faurholt-JepsenLars Vedel Kessing
Jan 8, 2016·JMIR Mental Health·Till BeiwinkelWulf Rössler
Jun 11, 2011·Comprehensive Psychiatry·Ana González-IsasiAna González-Pinto
Jun 12, 2010·Journal of Affective Disorders·A R RosaE Vieta
Nov 6, 2009·Journal of Psychiatric Research·Camilo J RuggeroDiane Young
Sep 24, 2015·Bipolar Disorders·Maria Faurholt-JepsenLars Vedel Kessing
Aug 18, 2009·Clinical Psychology : a Publication of the Division of Clinical Psychology of the American Psychological Association·David J Miklowitz, Sheri L Johnson
Dec 24, 2010·Bipolar Disorders·Colin A DeppThomas L Patterson
Apr 3, 2016·International Journal of Methods in Psychiatric Research·Maria Faurholt-JepsenLars Vedel Kessing
Aug 24, 2010·Comprehensive Psychiatry·Lauren M Weinstock, Ivan W Miller
May 20, 2015·Journal of Affective Disorders·C Mar BonnínEduard Vieta
Jul 26, 2011·Journal of Affective Disorders·Julia W Y KamColleen A Brenner
Sep 28, 2014·Journal of Affective Disorders·Lucas da Silva CostaModesto Leite Rolim Neto
Jul 30, 2010·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·Adriane R RosaEduard Vieta
Apr 1, 2014·Psychiatry Research·Maria Faurholt-JepsenLars Vedel Kessing
Jan 28, 2017·European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology·Jose Sanchez-MorenoUNKNOWN CIBERSAM Functional Remediation Group
Jul 21, 2016·Translational Psychiatry·M Faurholt-JepsenL V Kessing
Feb 11, 2015·The Journal of Nervous and Mental Disease·Rebecca S SiegelMartin B Keller
Nov 6, 2018·The Australian and New Zealand Journal of Psychiatry·Maria Faurholt-JepsenLars Vedel Kessing
Jul 17, 2010·Yonsei Medical Journal·Vin RyuJeong-Ho Seok
Apr 5, 2019·Psychological Medicine·Maria Faurholt-JepsenLars Vedel Kessing
May 17, 2019·The International Journal of Neuropsychopharmacology·Caterina Del Mar BonnínEduard Vieta
May 5, 2018·Acta Psychiatrica Scandinavica·J Sanchez-MorenoUNKNOWN CIBERSAM Functional Remediation Group
Jan 31, 2017·European Psychiatry : the Journal of the Association of European Psychiatrists·K E A SaundersG M Goodwin
Dec 8, 2020·Frontiers in Human Neuroscience·Anna Maria SobczakAdrian Andrzej Chrobak
Nov 3, 2020·International Journal of Bipolar Disorders·Sharleny StanislausMaria Faurholt-Jepsen
Oct 22, 2017·Journal of Affective Disorders·Imma TorresAnabel Martínez-Aran