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Functional Importance of Second Heart Field-derived Cells During Thoracic Aortic Aneurysm Formation

bioRxiv

Feb 2, 2020

Hisashi SawadaAlan Daugherty

Abstract

Embryonic origins of smooth muscle cells (SMCs) may contribute to regional specificity of thoracic aortic aneurysms. Here, we demonstrate that SMCs derived from the second heart field localized with angiotensin II-induced aortopathies. Proteomics analysis discerned potential roles of Lr...read more

Mentioned in this Paper

Embryo
Transforming Growth Factor beta
Aorta
Angiotensin A
LRP1 protein, human
Takayasu Arteritis
Signal Pathways
Myocytes, Smooth Muscle
Local
Gene Therapy
12
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Functional Importance of Second Heart Field-derived Cells During Thoracic Aortic Aneurysm Formation

bioRxiv

Feb 2, 2020

Hisashi SawadaAlan Daugherty

DOI: 10.1101/2020.02.02.930917

Abstract

Embryonic origins of smooth muscle cells (SMCs) may contribute to regional specificity of thoracic aortic aneurysms. Here, we demonstrate that SMCs derived from the second heart field localized with angiotensin II-induced aortopathies. Proteomics analysis discerned potential roles of Lr...read more

Mentioned in this Paper

Embryo
Transforming Growth Factor beta
Aorta
Angiotensin A
LRP1 protein, human
Takayasu Arteritis
Signal Pathways
Myocytes, Smooth Muscle
Local
Gene Therapy
12

Feeds With Similar Papers

Aortic Coarctation

Aortic coarctation is a congenital condition characterized by narrowing of the aorta. Discover the latest research on this disease here.

BioRxiv Preprints

BioRxiv is the preprint server for biology, operated by Cold Spring Harbor Laboratory. Here are the latest biology preprint articles from bioRxiv.

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