Functional informatics: convergence and integration of automation and bioinformatics

Pharmacogenomics
Sergey E IlyinHong Xin

Abstract

The biopharmaceutical industry is currently being presented with opportunities to improve research and business efficiency via automation and the integration of various systems. In the examples discussed, industrial high-throughput screening systems are integrated with functional tools and bioinformatics to facilitate target and biomarker identification and validation. These integrative functional approaches generate value-added opportunities by leveraging available automation and information technologies into new applications that are broadly applicable to different types of projects, and by improving the overall research and development and business efficiency via the integration of various systems.

References

Jan 1, 1991·Journal of Clinical Epidemiology·D J Deeg
Nov 27, 1998·Progress in Biophysics and Molecular Biology·G Schneider, P Wrede
May 29, 2000·Current Opinion in Chemical Biology·J Sadowski
Aug 10, 2000·Neural Networks : the Official Journal of the International Neural Network Society·G Schneider
Jan 28, 2003·Drug Discovery Today·Brian L Claus, Dennis J Underwood
Jan 28, 2003·Drug Discovery Today·Petra BurgstallerMichael Blind
Apr 12, 2003·Science·Francis S CollinsAristides Patrinos
Jul 12, 2003·Journal of Biomolecular Screening·Andrew L DarrowSergey E Ilyin
Nov 5, 2003·Proteomics·Barry SchweitzerMichael Snyder
Nov 25, 2003·Bioinformatics·Christos A Ouzounis, Alfonso Valencia
Dec 4, 2003·Biochemical Society Transactions·L A Soinov
Feb 12, 2004·Bioinformatics·GuoDong ZhouChewLim Tan
Mar 23, 2004·Combinatorial Chemistry & High Throughput Screening·Albert PinhasovSergey E Ilyin
Mar 30, 2004·Oncogene·Sandra PaveyNicholas K Hayward
Mar 31, 2004·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Yixin WangDavid Atkins
Apr 15, 2004·The Biochemical Journal·Gong-Hong WeiChih-Chuan Liang
Apr 15, 2004·Drug Discovery Today·Michael Hoever, Peter Zbinden
Jun 12, 2004·Journal of Biomolecular Screening·Hong XinSergey E Ilyin
Jun 23, 2004·Annals of the New York Academy of Sciences·Daniel R Rhodes, Arul M Chinnaiyan
Jul 31, 2004·Trends in Biotechnology·Sergey E IlyinCarlos R Plata-Salamán
Dec 8, 2004·Combinatorial Chemistry & High Throughput Screening·Derrick MaleySergey E Ilyin

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Citations

Jul 17, 2012·EURASIP Journal on Bioinformatics & Systems Biology·Kirk K DurstonGary Cl Li
Sep 8, 2007·Source Code for Biology and Medicine·Armin Lahm, Emanuele de Rinaldis
May 10, 2012·PLoS Computational Biology·Christos A Ouzounis
Jun 27, 2006·Journal of Immunotherapy·Bernard J ScallonMarian T Nakada

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