Functional interactions by transfer RNAs in the ribosome.

FEBS Letters
Prashant Khade, Simpson Joseph

Abstract

Recent X-ray crystal structures of the ribosome have revolutionized the field by providing a much-needed structural framework to understand ribosome function. Indeed, the crystal structures rationalize much of the genetic and biochemical data that have been meticulously gathered over 50 years. Here, we focus on the interactions between tRNAs and the ribosome and describe some of the insights that the structures provide about the mechanism of translation. Both high-resolution structures and functional studies are essential for fully appreciating the complex process of protein synthesis.

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Citations

Mar 23, 2015·FEMS Microbiology Reviews·Jennifer Shepherd, Michael Ibba
May 14, 2016·Molecular Microbiology·Assaf KatzMichael Ibba
Mar 2, 2012·Journal of the American Chemical Society·Carles Acosta-SilvaAntoni Oliva
Jun 4, 2020·Wiley Interdisciplinary Reviews. RNA·Shurong LiuJianhua Yang
Dec 25, 2019·Nature Structural & Molecular Biology·Dejian ZhouMatthieu G Gagnon
Jul 13, 2012·Chembiochem : a European Journal of Chemical Biology·Anna-Skrollan Geiermann, Ronald Micura
Oct 22, 2021·Journal of Molecular Biology·Sooin KimHyun Soo Lee

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