PMID: 11332459May 3, 2001Paper

Functional magnetic resonance imaging in children with Asperger's syndrome

Journal of Child Neurology
F OktemB Anlar

Abstract

Asperger's syndrome is a pervasive developmental disorder of unknown etiology. We evaluated children with this syndrome (n = 9) and control (n = 8) children by functional magnetic resonance imaging (MRI) during a task involving social judgment. All control and 5 of 9 subjects with Asperger's syndrome showed signal intensity changes in frontal regions. Four patients with Asperger's syndrome, including one case with right frontal dysplasia, had no signal intensity change during the task. In this first functional MRI study of childhood Asperger's syndrome, frontal activation patterns demonstrated some differences between patients and normal subjects. Further studies using other functions frequently impaired in Asperger's syndrome are warranted.

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Citations

Sep 26, 2003·Current Opinion in Pediatrics·Bellelizabeth Foster, Bryan H King
Mar 12, 2005·Cognitive and Behavioral Neurology : Official Journal of the Society for Behavioral and Cognitive Neurology·S G Shamay-TsooryJ Aharon-Peretz
Oct 18, 2014·Frontiers in Neurology·Alessandro G AllieviEtienne Burdet
Nov 22, 2016·Autism Research : Official Journal of the International Society for Autism Research·Anila M D'MelloCatherine J Stoodley
Nov 22, 2011·Neuroscience and Biobehavioral Reviews·Ruth C M PhilipAndrew C Stanfield

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Asperger Syndrome

Asperger syndrome (AS), also known as Asperger's, is a developmental disorder characterized by significant difficulties in social interaction and nonverbal communication, along with restricted and repetitive patterns of behavior and interests. Discover the latest research on Asperger syndrome here.

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