PMID: 9178251Jun 1, 1997Paper

Functional magnetic resonance imaging of median nerve stimulation in rats at 2.0 T

Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine
B E ScanleyJ C Gore

Abstract

An animal model of sensory activation using fMRI at 2.0 T has been developed, demonstrating that fMRI studies on animals need not be limited to high field magnets. These methods produced reliable image intensity changes of 2% using median nerve stimulation in rats at 3 Hz and propofol as the anesthetic agent. At 6 Hz the activation was slightly but not statistically significantly greater. The feasibility of fMRI studies in animals using propofol suggests that it may be a useful anesthetic for fMRI studies in agitated adult patients or in children.

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Citations

Mar 18, 1999·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·K M LahtiJ A King
Dec 18, 2001·Journal of Magnetic Resonance Imaging : JMRI·M HoehnB van der Sanden
Sep 5, 2002·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Michael V DutkaJohn C Gore
Dec 5, 1998·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·R P KennanJ C Gore
May 1, 1999·Journal of Neuroscience Methods·K M LahtiJ A King
Nov 11, 1998·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·N van BruggenA J de Crespigny
Jun 16, 2005·NeuroImage·Thomas GasserChristopher Nimsky
Mar 7, 2006·European Journal of Pain : EJP·Andreas HessKay Brune
Sep 20, 2000·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·R P KennanJ C Gore
Apr 16, 1999·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·G BrinkerM Hoehn-Berlage

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