Functional magnetic stimulation of the respiratory muscles in dogs

Muscle & Nerve
V W LinA F DiMarco

Abstract

This study assessed the ability of functional magnetic stimulation (FMS) to activate the respiratory muscles in dogs. With the animal supine, FMS of the phrenic nerves using a high-speed magnetic stimulator was performed by placing a round magnetic coil (MC) at the carotid triangle. Following hyperventilation-induced apnea, changes in volume (deltaV) and airway pressure (deltaP) against an occluded airway were determined. FMS of the phrenic nerves produced substantial inspired function (deltaV = 373 +/- 20.5 mL and deltaP = -20 +/- 2.0 cm H2O). After bilateral phrenectomies, maximal inspired deltaV (219 +/- 12.2 mL) and deltaP (-10 +/- 1.0 cm H2O) were produced when the MC was placed near the C6-C7 spinous processes, while maximal expired deltaV (-199 +/- 22.5 mL) and deltaP (11 +/- 2.3 cm H2O) were produced following stimulation near the T9-T10 spinous processes. We conclude: (1) FMS of either the phrenic or upper intercostal nerves results in inspired volume production; (2) FMS of the lower intercostal nerves generates expired volume production; and (3) FMS of the respiratory muscles may be a useful noninvasive tool for artificial ventilation and assisted cough in patients with spinal cord injuries or other neurological disor...Continue Reading

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Citations

Aug 8, 2007·Respiratory Physiology & Neurobiology·Anthony F DiMarcoJaroslaw R Romaniuk
Mar 13, 2016·PM & R : the Journal of Injury, Function, and Rehabilitation·Xiaoming ZhangVernon Lin
Jun 15, 2010·Muscle & Nerve·Björn H SanderKonstantinos Raymondos
Jan 24, 2006·IEEE Transactions on Neural Systems and Rehabilitation Engineering : a Publication of the IEEE Engineering in Medicine and Biology Society·Vernon Weh-Hau LinIan N Hsiao
Aug 21, 2008·IEEE Transactions on Neural Systems and Rehabilitation Engineering : a Publication of the IEEE Engineering in Medicine and Biology Society·Vernon W-H LinIan N Hsiao
Sep 18, 2004·Archives of Physical Medicine and Rehabilitation·Vernon W LinScott Sasse
Mar 10, 2001·Archives of Physical Medicine and Rehabilitation·V W LinI Perkash

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