Functional mapping of the periaqueductal gray matter involved in organizing tonic immobility behavior in guinea pigs

Behavioural Brain Research
Eveline Bis VieiraChristie Ramos Andrade Leite-Panissi

Abstract

Tonic immobility behavior (TI) is an innate response characterized by profound motor inhibition that is exhibited by prey when physical contact with a predator is prolonged and the situation inescapable. The periaqueductal gray matter (PAG) is intimately associated with the somatic and autonomic components of defensive reactions. This study investigated whether the TI response was able to recruit specific functional columns of the PAG by examining c-fos immunolocalization in guinea pigs. In the TI group, the innate response was invoked in animals through inversion and physical contention for at least 15 min. In the control group, the animals were physically manipulated only. Our results demonstrate that the defensive behavior of TI is capable of promoting the expression of Fos protein in different areas of the PAG, with higher levels of staining in the ventrolateral (vl) and lateral (l) columns. In addition, our results demonstrate increased Fos immunoreactivity (FOS-IR) in the dorsal raphe nucleus, the Edinger-Westphal nucleus, the cuneiform nucleus and the superior colliculus. In contrast, there were no significant alterations in the number of FOS-IR cells in the inferior colliculus or the oculomotor nucleus. Analysis of the ...Continue Reading

References

May 11, 1979·Brain Research·U Jürgens, R Pratt
Nov 22, 1991·The Journal of Comparative Neurology·R P Vertes
Jan 1, 1990·Neuroscience and Biobehavioral Reviews·R J BlanchardS M Weiss
Aug 1, 1969·Brain Research·G Carli
Jan 1, 1984·Annual Review of Neuroscience·A I Basbaum, H L Fields
Sep 18, 1995·The Journal of Comparative Neurology·N S CanterasL W Swanson
Dec 31, 1997·Brain Research. Brain Research Reviews·P Y Risold, L W Swanson
Dec 24, 1997·Journal of the Autonomic Nervous System·M F KlemmG D Hirst
Jan 14, 1998·Neuroreport·L de OliveiraL Menescal-de-Oliveira
Dec 14, 1999·Neuroscience and Biobehavioral Reviews·M L BrandãoV M Castilho
Nov 24, 1999·Brain Research Bulletin·C R MonassiL Menescal-de-Oliveira
Dec 22, 1999·Physiology & Behavior·C RamosL Menescal-De-Oliveira
Feb 15, 2001·Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas·C R Leite-PanissiL Menescal-De-Oliveira
Jul 18, 2002·Brain Research Bulletin·Christie Ramos Andrade Leite-Panissi, Leda Menescal-de-Oliveira
Dec 11, 2003·Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas·J A CavaniC A B Toledo
Apr 30, 2004·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Iain S McGregorGlenn E Hunt

❮ Previous
Next ❯

Citations

Jun 20, 2012·Brain Research·Claudia Herrera TambeliCarlos Amílcar Parada
Jun 23, 2011·Biological Psychology·Eliane VolchanIvan Figueira
Apr 23, 2013·Hormones and Behavior·Karina G BorelliMarcus L Brandão
Jul 23, 2016·Brain Structure & Function·Fernando Falkenburger MelleuJ Marino-Neto
May 7, 2016·Brain Research·Bruna Balbino de Paula, Christie Ramos Andrade Leite-Panissi
Jun 11, 2015·Harvard Review of Psychiatry·Kasia KozlowskaPascal Carrive
Jul 9, 2020·Proceedings. Biological Sciences·Ana B Sendova-FranksNigel R Franks
Jun 30, 2019·Journal of Neuroscience Research·Braeden A TerpouRuth A Lanius
Feb 13, 2019·Neuroscience Letters·Bruna B de PaulaChristie R A Leite-Panissi
May 26, 2021·Journal of Translational Medicine·Aymen H SadakaCraig F Ferris
Aug 28, 2021·Animals : an Open Access Journal From MDPI·Sophia E HoldsworthNgaio J Beausoleil

❮ Previous
Next ❯

Related Concepts

Related Feeds

Amygdala and Midbrain Dopamine

The midbrain dopamine system is widely studied for its involvement in emotional and motivational behavior. Some of these neurons receive information from the amygdala and project throughout the cortex. When the circuit and transmission of dopamine is disrupted symptoms may present. Here is the latest research on the amygdala and midbrain dopamine.

Amygdala: Sensory Processes

Amygdalae, nuclei clusters located in the temporal lobe of the brain, play a role in memory, emotional responses, and decision-making. Here is the latest research on sensory processes in the amygdala.