Functional modeling of pedaling kinematics for the Stroke patients.

Journal of Biopharmaceutical Statistics
Sounak ChakrabortySusan M Linder

Abstract

Understanding deficits in motor control through the analysis of pedaling biomechanics plays a key role in the treatment of stroke patients. A thorough study of the impact of different exercise patterns and workloads on the change between pre- and post-treatment movement patterns in the patients is therefore of utmost importance to the clinicians. The objective of this study was to analyze the difference between pre- and post-treatment pedaling torques when the patients are subject to different exercise groups with varying workloads. The effects of affected vs unaffected side along with the covariates age and BMI have also been accounted for in this work. Two different three-way ANOVA-based approaches have been implemented here. In the first approach, a random projection-based ANOVA technique has been performed treating the pedaling torques as functional response, whereas the second approach utilizes distance measures to summarize the difference between pre- and post-treatment torques and perform nonparametric tests on it. Bayesian bootstrap has been used here to perform tests on the median distance. A group of stroke patients have been studied in the Cleveland Clinic categorizing them into different exercise groups and workload...Continue Reading

References

Mar 20, 1998·Stroke; a Journal of Cerebral Circulation·D A Brown, S A Kautz
Aug 25, 1999·Journal of Biomechanics·W SmakM L Hull
Mar 8, 2008·Journal of Bioinformatics and Computational Biology·Minghui JiangBinhai Zhu
Feb 22, 2017·The American Journal of Occupational Therapy : Official Publication of the American Occupational Therapy Association·Susan M LinderJay L Alberts
Feb 16, 2018·Topics in Stroke Rehabilitation·Susan M LinderJay L Alberts
Jul 18, 2019·Neurorehabilitation and Neural Repair·Susan M LinderJay L Alberts

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FANOVA
R Shinny Application

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