PMID: 15235232Jul 6, 2004Paper

Functional neuroanatomy in depressed patients with sexual dysfunction: blood oxygenation level dependent functional MR imaging

Korean Journal of Radiology : Official Journal of the Korean Radiological Society
Jong-Chul Yang

Abstract

To demonstrate the functional neuroanatomy associated with sexual arousal visually evoked in depressed males who have underlying sexual dysfunction using Blood Oxygenation Level Dependent-based fMRI. Ten healthy volunteers (age range 21-55: mean 32.5 years), and 10 depressed subjects (age range 23-51: mean 34.4 years, mean Beck Depression Inventory score of 39.6+/-5.9, mean Hamilton Rating Scale Depression (HAMD)-17 score of 33.5+/-6.0) with sexual arousal dysfunction viewed erotic and neutral video films during functional magnetic resonance imaging (fMRI) with 1.5 T MR scanner (GE Signa Horizon). The fMRI data were obtained from 7 oblique planes using gradient-echo EPI (flip angle/TR/TE= 90 degrees /6000 ms/50 ms). The visual stimulation paradigm began with 60 sec of black screen, 150 sec of neutral stimulation with a documentary video film, 30 sec of black screen, 150 sec of sexual stimulation with an erotic video film followed by 30 sec of black screen. The brain activation maps and their quantification were analyzed by SPM99 program. There was a significant difference of brain activation between two groups during visual sexual stimulation. In depressed subjects, the level of activation during the visually evoked sexual arou...Continue Reading

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Citations

Sep 3, 2011·The Journal of Sexual Medicine·Sabine KagererRudolf Stark
Dec 12, 2012·The Journal of Sexual Medicine·Anita H ClaytonCarol R Reed
Dec 17, 2008·Psychiatry Research·John McLeanJonathan Cavanagh
Nov 28, 2007·Journal of Psychiatric Research·James M CantorRay Blanchard
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May 1, 2012·Lower Urinary Tract Symptoms·Takashi ItoTatsuya Yamamoto
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Dec 20, 2012·Psychiatry Investigation·Jong-Chul YangGwang-Woo Jeong
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Sep 20, 2018·International Journal of Impotence Research·José Nuno Trovão, Ege Can Serefoglu
Feb 18, 2020·Revista Internacional De Andrología·Babak Hosseinzadeh ZoroufchiAbolfazl Abdollahpour

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