Functional Neurologic Symptom Disorder in Children: Clinical Features, Diagnostic Investigations, and Outcomes at a Tertiary Care Children's Hospital

Journal of Child Neurology
Carla WatsonRajkumar Agarwal

Abstract

To describe the presenting symptoms and short-term outcomes of children diagnosed with functional neurologic symptom disorder and to compare the demographic and clinical characteristics of children who received neurodiagnostic testing to those who did not. Single center, retrospective review of 222 children who presented to the emergency department of a children's hospital, and diagnosed with functional neurologic symptom disorder, between 2010 and 2015. Out of 222 visits (females = 156, African Americans = 130, mean age = 13.9 years), neurodiagnostic tests were performed in 102/222 (46%) visits. The most commonly performed investigations were magnetic resonance imaging (MRI) of brain (n = 37) and electroencephalogram (EEG) (n = 56) and were noted to be unremarkable in all instances. Neurodiagnostic tests were more likely to be performed in patients who (1) were non-African American (54% vs 40%; P = .03), (2) presented with new-onset symptoms (55% vs 31%; P < .01), (3) underwent hospitalization (61% vs 17%; P < .01), and (4) were evaluated by a neurologist (59% vs 9%; P < .01) or a psychiatrist (58% vs 28%; P < .01). Common clinical presentations included seizurelike or strokelike symptoms. Short-term follow-up was possible in ...Continue Reading

References

Apr 1, 1989·Neurology·J R Keane
Jan 1, 1982·Neurology·T A GulickD W King
Oct 3, 1999·Journal of the American Academy of Child and Adolescent Psychiatry·J V CampoK J Kelleher
Mar 15, 2000·Postgraduate Medical Journal·S Beatty
Apr 20, 2000·The New England Journal of Medicine·J H PopeH P Selker
Jan 30, 2002·Psychosomatics·J V Campo, G Fritz
Aug 20, 2002·Journal of Neurology, Neurosurgery, and Psychiatry·J StoneM Sharpe
Jun 14, 2006·Neurology·Steve S ChungKristin A Kirlin
Jan 2, 2007·Journal of the American Academy of Child and Adolescent Psychiatry·Kasia KozlowskaJohn Varghese
Feb 3, 2007·Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine·Liliana E PezzinGary B Green
Apr 23, 2009·International Journal of Emergency Medicine·Daniel J PallinCarlos A Camargo
Aug 13, 2011·Genetics in Medicine : Official Journal of the American College of Medical Genetics·Caleb HoltzerChristopher Cunniff
Apr 27, 2013·The British Journal of Psychiatry : the Journal of Mental Science·Cornelius AniElena Garralda
Sep 26, 2014·Neurosurgery·Ammar H HawasliRalph G Dacey
Oct 17, 2016·Pediatric Neurology·Amy M DeLarocheNirupama Kannikeswaran

❮ Previous
Next ❯

Citations

Nov 14, 2020·European Journal of Pediatrics·Aaron WigginsSusan M Sawyer
Aug 11, 2021·Current Problems in Pediatric and Adolescent Health Care·Rajkumar AgarwalHara Stephanou
May 29, 2021·The Journal of Nervous and Mental Disease·Ehsan Nikrad, Richard A Kanaan

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Pediatric Neurology
Megan BarryLori C Jordan
Neurología : publicación oficial de la Sociedad Española de Neurología
I García-MoralesA Gil-Nagel
Revista de investigación clínica; organo del Hospital de Enfermedades de la Nutrición
Teresa CoronaMayela Rodríguez-Violante
© 2022 Meta ULC. All rights reserved