Functional outcome and quality of life 5 and 12.5 years after aneurysmal subarachnoid haemorrhage.

Journal of Neurology
Paut GreebeA Algra

Abstract

Patients who recover from aneurysmal subarachnoid haemorrhage (SAH) often remain disabled or have persisting symptoms with a reduced quality of life (QoL). We assessed functional outcome and QoL 5 and 12.5 years after SAH. In a consecutive series of 64 patients with mean age at SAH of 51 years, initial outcome assessments had been performed at 4 and 18 months after SAH. At the initial and current outcome assessments, functional outcome was measured with the modified Rankin Scale (mRS) and QoL with the SF-36 and a visual analogue scale (VAS). We studied the change in outcome measurements over time. We used the non-parametric Wilcoxon test to compare differences in mRS grades and calculated differences with corresponding 95% confidence intervals in the domain scores of the SF-36 and the VAS. After 5 years, seven patients had died and five patients had missing data. Compared with the 4-month follow-up, the mRS had improved in 29 of the 52 patients, remained similar in 19 patients. The overall QoL (SF-36 domains and VAS score) was better. At 12.5 years an additional six patients had died. Compared to the 4-month study, 25 of the 46 remaining patients had improved mRS, 12 had remained the same and in nine patients the mRS had worsen...Continue Reading

References

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Citations

May 18, 2012·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·K MalmivaaraJ Siironen
Oct 2, 2012·World Neurosurgery·Martin TjahjadiThomas Kapapa
Sep 17, 2013·Rehabilitation Nursing : the Official Journal of the Association of Rehabilitation Nurses·Bogdan CzapigaMalgorzata Krautwald-Kowalska
Apr 18, 2015·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Matthias PonfickDennis A Nowak
Sep 5, 2017·Acta Neurologica Scandinavica·H C PerssonK S Sunnerhagen
Jul 3, 2018·Acta Neurologica Scandinavica·D RackauskaiteB Nellgård
Jul 3, 2013·Stroke; a Journal of Cerebral Circulation·Edeltraut GarbeSigrid Behr
Mar 28, 2017·Stroke; a Journal of Cerebral Circulation·Kevin PhanAjith J Thomas
Aug 2, 2012·The Journal of Clinical Endocrinology and Metabolism·Luca Persani
Jun 27, 2014·Clinical Endocrinology·M J HannonC J Thompson
Oct 1, 2015·Neurosurgery·Zahrah TaufiqueJ Michael Schmidt
Apr 22, 2020·Aging·Alexander HammerHendrik Janssen
Jun 4, 2013·Neurosurgery·Hendrik Koffijberg

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