Functional outcome in TBI II: verbal memory and information processing speed mediators

Journal of Clinical and Experimental Neuropsychology
Yuri RassovskyDavid Hovda

Abstract

Following traumatic brain injury (TBI), patients often report memory difficulties, as well as reduced information processing speed. However, it remains unclear the extent to which these deficits contribute to functional impairment. In the present study, we compared the relative contribution of verbal memory and information processing speed to functional impairment at 12-month post-injury, in 87 patients with moderate-to-severe TBI. Employing structural equation modeling, we found that information processing speed, but not verbal memory functions, significantly mediated the relationship between TBI severity and post-TBI adaptive functioning. These findings suggest that despite the pervasive memory complaints among patients with TBI, it is the impact of neurotrauma on frontal systems that appears to be primarily responsible for patients' difficulties in social and occupational functioning.

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Citations

Dec 23, 2008·Archives of Physical Medicine and Rehabilitation·Robin E GreenGeorges Monette
Aug 4, 2010·Journal of Clinical and Experimental Neuropsychology·Paul SatzYuri Rassovsky
Jun 30, 2012·The British Journal of Psychiatry : the Journal of Mental Science·Jennifer J VasterlingMolly Franz
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Aug 31, 2010·Archives of Physical Medicine and Rehabilitation·Marieke R BenedictusJoukje van der Naalt
Apr 3, 2015·Journal of Clinical and Experimental Neuropsychology·Yuri RassovskyEli Vakil
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Feb 9, 2013·Journal of Clinical and Experimental Neuropsychology·Kelly L SinclairClare Anderson
Jul 7, 2017·Neuropsychology Review·Fiona AllansonMichael Weinborn
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Software Mentioned

EQS Structural Equation Package

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Brain Injury & Trauma

brain injury after impact to the head is due to both immediate mechanical effects and delayed responses of neural tissues.

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