Functionalization of Lipid-Based Nutrient Supplement with β-Cyclodextrin Inclusions of Oregano Essential Oil

Journal of Food Science
Shashank GaurJuan E Andrade

Abstract

Intestinal parasitic infection is one of the main causes of acute undernutrition in children. Oral consumption of oregano essential oil (OEO) can reduce intestinal parasitic infections, however, its addition to therapeutic and supplementary foods is hampered by its undesirable flavor. The objective of this study was to develop a functional lipid-based nutrient supplement (LNS) containing OEO, which is stable, acceptable and provides targeted intestinal delivery of bioactive. β-cyclodextrin (β-CyD) inclusion complexes of OEO (β-CyD-OEO), and carvacrol (β-CyD-CV) (1:1 molar) were prepared using slurry complexation (-20 °C) method and characterized based on encapsulation efficiency, moisture content, morphology, and 2-phase in vitro digestion stability. Carvacrol (CV) content was measured using reverse phase HPLC-UV. LNS containing β-CyD-OEO (27.2 mg encapsulate/20 g LNS) was formulated using Indian staples and ingredients. Discriminatory sensory tests (triangle) were performed with college students (n = 58) and low-income women (n = 25), with young children at home (1 to 6 years), living in Mehsana, India to evaluate differences between LNS with and without bioactive ingredient (β-CyD-OEO only). Moisture of dried complexes ranged...Continue Reading

References

Oct 1, 1981·The American Journal of Clinical Nutrition·D D MillerD Van Campen
Jun 1, 1995·Regulatory Toxicology and Pharmacology : RTP·J B Hallagan, R L Hall
Dec 10, 1999·Journal of Agricultural and Food Chemistry·D A GarrettR J Sarama
May 18, 2000·Phytotherapy Research : PTR·M ForceR A Ronzio
Jun 6, 2000·Advanced Drug Delivery Reviews·F Hirayama, K Uekama
Dec 22, 2000·The American Journal of Clinical Nutrition·C A Northrop-ClewesP G Lunn
Aug 4, 2001·Parasite : Journal De La Société Française De Parasitologie·J J García-RodriguezF Bolás
May 16, 2002·Revista Da Sociedade Brasileira De Medicina Tropical·Maria Imaculada Muniz-Junqueira, Eduardo Flávio Oliveira Queiroz
Jul 3, 2002·Journal of Clinical Pharmacology·Claudia KohlertMarkus Veit
Apr 1, 2004·Journal of Agricultural and Food Chemistry·Avinash KantAndrew J Taylor
Aug 16, 2005·International Journal of Pharmaceutics·Thorsteinn LoftssonMár Másson
Nov 28, 2006·Journal of Chromatography. a·Yu YangAhmet M Gizir
Jan 22, 2008·Lancet·Robert E BlackUNKNOWN Maternal and Child Undernutrition Study Group
Aug 30, 2008·Nutrition Reviews·Richard L GuerrantAldo A M Lima
Oct 25, 2008·Critical Reviews in Food Science and Nutrition·David Julian McClementsYeonhwa Park
Dec 17, 2008·Current Pharmaceutical Design·K Husnu Can Baser
May 4, 2011·Journal of Food Science·Lauren C TamamotoSoo-Yeun Lee
Jan 10, 2010·Food & Function·David Julian McClements, Yan Li
Sep 11, 2012·Journal of Agricultural and Food Chemistry·Maxine J RomanR Paul Singh
Dec 5, 2013·Carbohydrate Polymers·Eva PinhoMariana Henriques

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