Functioning methionine-S-sulfoxide reductases A and B are present in human skin

The Journal of Investigative Dermatology
Karin U Schallreuter

Abstract

Methionine residues in the structure of proteins and peptides are especially sensitive to oxidation by hydrogen peroxide (H(2)O(2)) yielding both the (R) and (S) diastereomers of methionine sulfoxide. This commentary shows that both diastereomers of methionine sulfoxide (R and S) can be repaired in the human epidermis by methionine sulfoxide reductases A and B, respectively.

References

Nov 8, 1994·Proceedings of the National Academy of Sciences of the United States of America·M K ShigenagaB N Ames
Dec 1, 2001·Free Radical Biology & Medicine·J Nordberg, E S Arnér
Dec 18, 2001·Journal of Photochemistry and Photobiology. B, Biology·K U Schallreuter, J M Wood
Jun 1, 2002·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Alfred HanselStefan H Heinemann
Sep 17, 2002·Antioxidants & Redox Signaling·Akira MitsuiJunji Yodoi
Feb 11, 2005·JAMA : the Journal of the American Medical Association·Sarah RingoldRichard M Glass
May 10, 2005·Science·Samuel E SchrinerPeter S Rabinovitch
Mar 4, 2006·The Journal of Investigative Dermatology·Fumihide OgawaJens J Thiele

❮ Previous
Next ❯

Citations

Sep 2, 2006·The Journal of Investigative Dermatology·Jennifer D SpencerKarin U Schallreuter
Oct 19, 2007·The Journal of Investigative Dermatology·Karin U SchallreuterJohn M Wood
Nov 13, 2007·Free Radical Biology & Medicine·Karin U SchallreuterJohn M Wood
Mar 11, 2008·Experimental Dermatology·Mohammad ShalbafKarin U Schallreuter
Oct 21, 2010·Pigment Cell & Melanoma Research·Karin U SchallreuterHartmut Rokos
Oct 21, 2010·Clinical Science·Steven J Glassman
Feb 17, 2006·Biochemical and Biophysical Research Communications·Karin U SchallreuterJohn M Wood
Nov 17, 2006·The Journal of Investigative Dermatology·Nicholas C J GibbonsKarin U Schallreuter
Feb 25, 2009·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·J M WoodK U Schallreuter
Apr 21, 2009·Biochimica Et Biophysica Acta·Jose Luis Munoz-MunozJose Neptuno Rodríguez-López

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.