Functioning of older, long-term cancer survivors: the role of cancer and comorbidities

Journal of the American Geriatrics Society
Gary T DeimlingKaren F Bowman

Abstract

To examine the relative effect of comorbidities, noncancer symptoms, and cancer-related factors on the functioning of older adult long-term survivors of breast, colorectal, and prostate cancers. Data from in-person interviews with survivors of a tumor registry-based stratified random sample were used to test a multivariate model using ordinary least-squares regression. Survivors were identified in the tumor registry of a National Cancer Institute-designated Comprehensive Cancer Center in Cleveland, Ohio. Three hundred twenty-one older (>or=60), long-term (>or=5 years) cancer survivors. The primary outcome measure, functional difficulty, was measured using Nagi's Performance Limitations Index. Predictors included a number of indicators of survivors' personal characteristics, age-related health characteristics, and cancer-related characteristics. The model explained 44% of the variance in functional difficulties between the cancer survivors in this sample. The strongest predictors were symptoms not attributed to cancer (beta=0.28) and comorbidities (beta=0.22), although cancer-related factors explained an additional 8% of the variance over that explained by demographic and noncancer health factors, with current cancer-related sym...Continue Reading

References

Sep 1, 1985·Journal of the American Geriatrics Society·L K George, G G Fillenbaum
Feb 19, 2000·Hematology/oncology Clinics of North America·R Yancik, L A Ries
Feb 1, 2003·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Maria HewittRosemary Yancik
Aug 2, 2003·Journal of Rehabilitation Medicine·Veronika Fialka-MoserMichael Quittan

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Citations

Dec 13, 2012·Journal of Cancer Survivorship : Research and Practice·Mary SehlPatricia A Ganz
Dec 3, 2013·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Lisa GallicchioKathy J Helzlsouer
Aug 21, 2014·Journal of General Internal Medicine·Mara A SchonbergEdward R Marcantonio
Jun 19, 2012·Journal of Geriatric Oncology·Harvey Jay CohenAlice B Kornblith
May 3, 2011·European Journal of Oncology Nursing : the Official Journal of European Oncology Nursing Society·Lanell M BelluryJane Clark
Dec 3, 2014·Journal of Geriatric Oncology·Lisa K SprodKaren M Mustian
Sep 24, 2010·Journal of the National Cancer Institute·Harvey Jay Cohen
Jun 30, 2015·Health Services Research and Managerial Epidemiology·Allison ChristianJeanne Ferrante
Jul 3, 2010·Journal of Aging and Health·Karen F BowmanElizabeth E O'Toole
Dec 16, 2017·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Stephen J CarterLaura Q Rogers
Jul 16, 2011·Cancer Nursing·Victoria Wochna Loerzel, Karen Aroian
Oct 28, 2019·Cancer Causes & Control : CCC·Cindy K BlairAnita Y Kinney
Jul 26, 2019·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Shaila M StrayhornYamilé Molina
Jan 15, 2013·Journal of Psychosocial Oncology·Victoria Wochna Loerzel, Karen Aroian
Oct 17, 2014·Journal of Cancer Survivorship : Research and Practice·Corinne R LeachJulia H Rowland
Mar 25, 2017·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·I-Chan HuangKevin R Krull
Mar 5, 2021·Contemporary Clinical Trials Communications·Cindy K BlairWendy Demark-Wahnefried

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