PMID: 1617602Jul 15, 1992Paper

Functioning ovarian carcinoids induce severe constipation

Cancer
T MotoyamaH Shibuya

Abstract

Five patients with ovarian carcinoid who had severe constipation for a long period preoperatively showed marked reduction of this symptom postoperatively. Because this phenomenon was believed to be caused by some biologically active substance rather than a mechanical effect of the tumor, reactivity to 17 amine and peptide hormones was studied immunohistochemically in these patients. Numerous peptide YY (PYY)-positive cells were detected, with PYY-positive cells representing more than 50% of all carcinoid tumor cells in each patient. PYY, which has a pharmacologic inhibitory action on intestinal motility, was presumably the cause of the constipation in these patients.

References

Jan 1, 1986·Virchows Archiv. A, Pathological Anatomy and Histopathology·N Kimura, N Sasano
May 1, 1987·Acta Pathologica Japonica·M HayashiG Ohta
Jan 1, 1986·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·N KimuraT Namiki
Jan 1, 1983·Virchows Archiv. A, Pathological Anatomy and Histopathology·E WilanderT W Schwartz
Jan 1, 1984·Journal of Cancer Research and Clinical Oncology·A Talerman
Jul 1, 1982·Proceedings of the National Academy of Sciences of the United States of America·J M LundbergB Hamberger
May 1, 1982·American Journal of Clinical Pathology·T M UlbrightC E Ehrlich
Jan 1, 1981·The American Journal of Surgical Pathology·H MurayamaT Imai

❮ Previous
Next ❯

Citations

Feb 1, 1996·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·J H RenS C Huang
Feb 5, 2002·Peptides·William W Tseng, Carson D Liu
Mar 1, 2003·Pathology International·Nanae UtsumiTeiichi Motoyama
Mar 17, 2010·Journal of Minimally Invasive Gynecology·Chien-Wen ChenDaw-Yuan Chang
Dec 30, 2006·Peptides·Helen M Cox
Dec 5, 2006·Autonomic Neuroscience : Basic & Clinical·Helen M Cox
Jun 21, 2007·The Journal of Obstetrics and Gynaecology Research·Kouichiro KawanoToshiharu Kamura
May 9, 2012·The Journal of Obstetrics and Gynaecology Research·Eriko TakatoriToru Sugiyama
Jul 6, 2010·The Journal of Obstetrics and Gynaecology Research·Takumi KurabayashiTeiichi Motoyama
Jan 1, 2012·Gynecologic Oncology Case Reports·Munekage YamaguchiHidetaka Katabuchi
Dec 3, 2015·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·Chimeddulam ErdenebaatarHidetaka Katabuchi
Jul 13, 2016·Journal of the Egyptian National Cancer Institute·Islam H MetwallyReham M Abdelghani
Jan 1, 2011·Journal of Surgical Case Reports·G KachhawaJ Sharma
Jun 29, 2017·Gynecologic Oncology·Mathieu ViauMarie Plante
Nov 27, 2019·Medicine·Wei ChaiGuifeng Jia
Aug 1, 2018·Expert Review of Endocrinology & Metabolism·Agedi N Boto, Pei Hui

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.