Fundamental relations between short-term RR interval and arterial pressure oscillations in humans

Circulation
J A Taylor, D L Eckberg

Abstract

One of the principal explanations for respiratory sinus arrhythmia is that it reflects arterial baroreflex buffering of respiration-induced arterial pressure fluctuations. If this explanation is correct, then elimination of RR interval fluctuations should increase respiratory arterial pressure fluctuations. We measured RR interval and arterial pressure fluctuations during normal sinus rhythm and fixed-rate atrial pacing at 17.2+/-1.8 (SEM) beats per minute greater than the sinus rate in 16 healthy men and 4 healthy women, 20 to 34 years of age. Measurements were made during controlled-frequency breathing (15 breaths per minute or 0.25 Hz) with subjects in the supine and 40 degree head-up tilt positions. We characterized RR interval and arterial pressure variabilities in low-frequency (0.05 to 0.15 Hz) and respiratory-frequency (0.20 to 0.30 Hz) ranges with fast Fourier transform power spectra and used cross-spectral analysis to determine the phase relation between the two signals. As expected, cardiac pacing eliminated beat-to-beat RR interval variability. Against expectations, however, cardiac pacing in the supine position significantly reduced arterial pressure oscillations in the respiratory frequency (systolic, 6.8+/-1.8 to...Continue Reading

References

May 1, 1977·Medical & Biological Engineering & Computing·O RompelmanR I Kitney
Nov 1, 1975·Journal of Applied Physiology·P G Katona, F Jih
Nov 1, 1991·Clinical and Experimental Pharmacology & Physiology·J L ElghoziA Girard
May 1, 1990·The Journal of Clinical Investigation·T R PorterP K Mohanty
Mar 1, 1974·The American Journal of Physiology·G Preiss, C Polosa
Oct 1, 1971·Nature·B W HyndmanB M Sayers
Feb 15, 1995·The Journal of Physiology·J A TaylorD L Eckberg
Oct 1, 1994·The American Journal of Physiology·P BoutouyrieS Laurent
Apr 1, 1994·The American Journal of Physiology·H Rasgado-FloresJ DeSantiago
Dec 1, 1993·Cardiovascular Research·R FurlanA Malliani
Mar 1, 1993·The Journal of Physiology·R A FrankelS L Britton
Sep 1, 1993·Journal of the American College of Cardiology·M PaganiA Malliani

❮ Previous
Next ❯

Citations

Aug 23, 2000·Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society·Y P WangS K Tsai
Jan 17, 2002·Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society·D ZieglerJ L Elghozi
Aug 16, 2001·Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society·G GulliA Cevese
Aug 29, 2001·Medical & Biological Engineering & Computing·I KorhonenV Turjanmaa
Aug 29, 2001·Medical & Biological Engineering & Computing·J C EcheverríaB R Hayes-Gill
Nov 28, 2002·Medical & Biological Engineering & Computing·L FaesR Antolini
Aug 9, 2005·European Journal of Applied Physiology·S Carrasco-SosaOscar Yáñez-Suárez
May 30, 2006·Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society·Tulio Diaz, J Andrew Taylor
Feb 4, 2010·Medical & Biological Engineering & Computing·Abdugheni KutlukMasashi Kawamoto
Mar 30, 2005·Autonomic Neuroscience : Basic & Clinical·Kevin J FormesXiangrong Shi
May 3, 2002·Journal of the American College of Cardiology·Padmini Kaushal, J Andrew Taylor
Aug 23, 2001·Autonomic Neuroscience : Basic & Clinical·C W MyersJ A Taylor
Sep 21, 2002·Autonomic Neuroscience : Basic & Clinical·Luigina GuastiSergio Cerutti
Dec 15, 2000·Acta Physiologica Scandinavica·M A CustaudJ O Fortrat
Jun 13, 2002·Clinical and Experimental Pharmacology & Physiology·D RamaekersA E Aubert
Nov 15, 2007·Telemedicine Journal and E-health : the Official Journal of the American Telemedicine Association·Mara MalacarneMassimo Pagani
Jun 4, 2004·Journal of Cardiovascular Pharmacology·Tom A KuuselaTimo J Kaila
Jul 17, 2013·Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences·Norbert MarwanJürgen Kurths
Feb 14, 2006·Cephalalgia : an International Journal of Headache·F EbingerD Rating
Jun 2, 2000·Pacing and Clinical Electrophysiology : PACE·M V PitzalisP Rizzon
Oct 12, 2000·Pacing and Clinical Electrophysiology : PACE·D WichterleM Malík
Oct 3, 2006·American Journal of Physiology. Heart and Circulatory Physiology·Robert J BrychtaAndré Diedrich
Feb 23, 2010·American Journal of Physiology. Heart and Circulatory Physiology·Can Ozan Tan, J Andrew Taylor
Aug 3, 2012·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Masashi IchinoseDonal S O'Leary
May 8, 2009·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Rong ZhangBenjamin D Levine
Mar 18, 2005·Theoretical Biology & Medical Modelling·Bernhard M Schmitt
Apr 6, 2004·Medicine and Science in Sports and Exercise·Francois CottinVéronique Billat
Jul 14, 2010·Circulation Journal : Official Journal of the Japanese Circulation Society·Motohisa OsakaTakao Katoh
Feb 23, 2007·Biomedizinische Technik. Biomedical Engineering·Martin GlosIngo Fietze
Jul 7, 2011·Biomedizinische Technik. Biomedical Engineering·Alessandro BedaMarcelo Gama de Abreu
Oct 17, 2013·Applied Psychophysiology and Biofeedback·Helmut K LacknerIlona Papousek
Jun 19, 2012·Journal of Ayurveda and Integrative Medicine·Krishnan MuralikrishnanFehmida Visnegarawla
Jul 1, 2011·Psychosomatic Medicine·Amit Jasvant ShahViola Vaccarino
Sep 27, 2001·Psychosomatic Medicine·H SchächingerW Langewitz
Aug 19, 2014·Autonomic Neuroscience : Basic & Clinical·Lei Cao, Paul M Pilowsky
Mar 29, 2014·Medical & Biological Engineering & Computing·Dingchang ZhengAlan Murray
Mar 22, 2003·Journal of Speech, Language, and Hearing Research : JSLHR·Kevin J Reilly, Christopher A Moore
Feb 26, 2010·Psychology, Health & Medicine·D E AndersonB G Windham
Oct 11, 2001·Journal of Hypertension·P B PerssonG Parati

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiology Journals

Discover the latest cardiology research in this collection of the top cardiology journals.

Arrhythmia

Arrhythmias are abnormalities in heart rhythms, which can be either too fast or too slow. They can result from abnormalities of the initiation of an impulse or impulse conduction or a combination of both. Here is the latest research on arrhythmias.

Atrial Fibrillation

Atrial fibrillation is a common arrhythmia that is associated with substantial morbidity and mortality, particularly due to stroke and thromboembolism. Here is the latest research.