PMID: 3771980Nov 1, 1986Paper

Fundic atrophic gastritis in an elderly population. Effect on hemoglobin and several serum nutritional indicators

Journal of the American Geriatrics Society
S D KrasinskiS C Hartz

Abstract

The ratio of pepsinogen I to pepsinogen II in the circulation decreases progressively with increasing severity of atrophic gastritis of the fundic gland mucosa. Fasting blood was obtained from 359 free-living and institutionalized elderly people (age range, 60 to 99 years). A pepsinogen I/pepsinogen II ratio less than 2.9, indicating atrophic gastritis, was found in 113 (31.5%) subjects. The prevalence of atrophic gastritis increased significantly with advancing age (P less than .05). Within the atrophic gastritis group, 84 had a pepsinogen I level greater than or equal to 20 micrograms/L, indicating mild to moderate atrophic gastritis, and 29 had a pepsinogen I level less than 20 micrograms/L, indicating severe atrophic gastritis or gastric atrophy. A significant increase in the prevalences of elevated serum gastrin levels (P less than .005), low serum vitamin B12 levels (P less than .005), circulating intrinsic factor antibody (P less than .005), and anemia (P less than .025) was observed with stepwise increases in severity of atrophic gastritis. Subjects with atrophic gastritis exhibited a lower mean serum vitamin B12 level (P less than .05) and a higher mean folate level (P less than .05), but no difference was detected in ...Continue Reading

References

Oct 1, 1976·Clinical Science and Molecular Medicine·J F MacKenzie, R I Russell
Jan 1, 1976·Acta Medica Scandinavica·L ElsborgP Bastrup-Madsen
Jun 18, 1966·Lancet·A V HoffbrandD L Mollin
Nov 1, 1971·British Journal of Haematology·P C ElwoodA C Frazer
Jun 30, 1965·Annals of the New York Academy of Sciences·W J IrvineA W Williams
Jun 1, 1967·The American Journal of Clinical Nutrition·S G Schade, R F Schilling
Feb 12, 1970·The New England Journal of Medicine·J E McGuigan, W L Trudeau
Feb 1, 1970·Clinical Science·R Bluestone, L S Goldberg
Apr 1, 1970·Journal of the American Geriatrics Society·H Meindok, R Dvorsky
Jan 16, 1971·British Medical Journal·A BennM E Smith
Apr 3, 1971·British Medical Journal·M G KormanJ Hansky
May 1, 1968·Australasian Annals of Medicine·B Ungar
Jan 1, 1968·Scandinavian Journal of Gastroenterology·M SiuralaM Kekki
Sep 8, 1966·The New England Journal of Medicine·S G SchadeR F Schilling
Mar 1, 1984·The American Journal of Clinical Nutrition·R YipP R Dallman
Nov 1, 1982·The American Journal of Clinical Nutrition·S R LynchJ D Cook
Jul 1, 1955·Proceedings of the Society for Experimental Biology and Medicine·W P BOGERJ L CIMINERA
Apr 1, 1956·Journal of Gerontology·B F CHOWK OKUDA
Jul 1, 1961·Journal of Clinical Pathology·A H WATERS, D L MOLLIN
Mar 10, 1960·Acta Medica Scandinavica·M SIURALAW NYBERG
Jun 1, 1962·The Journal of Clinical Investigation·V HERBERT, R ZALUSKY
Jul 1, 1963·British Journal of Haematology·A H WATERS, D L MOLLIN
May 1, 1964·Scottish Medical Journal·P W KERSHAW, R H GIRDWOOD
Mar 1, 1964·Journal of Applied Physiology·P JACOBSR W CHARLTON
Mar 11, 1965·The New England Journal of Medicine·J M FISHER, K B TAYLOR
Feb 1, 1965·Gut·N F COGHILLA W WILLIAMS
Dec 28, 1959·Acta Medica Scandinavica·P G REIZENSTEIN

❮ Previous
Next ❯

Citations

Jun 16, 2006·Expert Opinion on Drug Safety·Julie A SchneiderMartha Clare Morris
Aug 26, 2010·Clinica Chimica Acta; International Journal of Clinical Chemistry·Bhawna Singh, Sarika Arora
Nov 17, 2009·The American Journal of Geriatric Psychiatry : Official Journal of the American Association for Geriatric Psychiatry·Edmund D HongDavid C Steffens
Mar 15, 2006·International Journal of Nursing Practice·Sonya Brownie
Jul 29, 2009·International Journal of Cancer. Journal International Du Cancer·Lei GaoHermann Brenner
Dec 2, 2009·The American Journal of Pathology·Carine Bossenmeyer-PouriéBernard Beck
Nov 13, 2004·Preventive Medicine·Maike WoltersAndreas Hahn
Jun 15, 2004·Clinica Chimica Acta; International Journal of Clinical Chemistry·Takahiro Mitsui, Takaharu Kondo
Apr 1, 1994·Metabolism: Clinical and Experimental·M E Melton, M L Kochman
Sep 1, 1995·Baillière's Clinical Haematology·J H Matthews
May 1, 1987·Journal of the American Geriatrics Society·M A Supiano
Apr 11, 2015·The British Journal of Nutrition·Rhona CreeganStephanie R Rainey-Smith
Mar 1, 1991·Journal of the American Geriatrics Society·I R BellJ O Cole
Dec 15, 2005·BMC Geriatrics·Lina PaulionisKelly A Meckling
Jan 15, 2015·Zeitschrift für Gerontologie und Geriatrie·A H Leischker, G F Kolb
Apr 27, 2016·Annals of the New York Academy of Sciences·Katherine L Tucker
Apr 25, 2000·Annual Review of Medicine·R Carmel
Jun 11, 2004·Annual Review of Nutrition·Sally P Stabler, Robert H Allen
Aug 17, 1999·Annual Review of Nutrition·H W Baik, R M Russell
Sep 1, 1996·Digestive Diseases and Sciences·A G PenneyP E O'Brien
Nov 12, 2002·Clinics in Geriatric Medicine·Swarnalatha Meyyazhagan, Robert M Palmer
Jul 4, 2001·Gastroenterology Clinics of North America·J D Linder, C M Wilcox
Jan 4, 2017·Scientific Reports·Tse-Ya YuHung-Yuan Li
Jan 11, 2014·American Journal of Alzheimer's Disease and Other Dementias·Yadollah Abolfathi MomtazRahimah Ibrahim
Dec 31, 2008·Journal of Intensive Care Medicine·Margaret A Pisani
Aug 20, 2008·Food and Nutrition Bulletin·Lindsay H Allen
Aug 31, 2004·World Journal of Gastroenterology : WJG·Jian-Min SiMin Gao
Aug 6, 1998·Alimentary Pharmacology & Therapeutics·S P PereiraR H Dowling
Oct 16, 2004·European Journal of Clinical Nutrition·T J GreenS M Williams
Jan 19, 2019·Molecular Nutrition & Food Research·Alexander StröhleUNKNOWN German Nutrition Society (DGE)
Aug 11, 2007·International Journal of Cancer. Journal International Du Cancer·Hermann BrennerMelanie N Weck
Jul 1, 1993·Journal of Gastroenterology and Hepatology·W C You, Y S Chang
Nov 1, 1989·Digestive Diseases and Sciences·D HollanderH Gergely
Jul 30, 2003·Clinical Pharmacokinetics·Thomas Lenz, Amy Wilson

❮ Previous
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