Fungal BRCA2 ortholog Brh2 brings 5' end strand invasion back on stage.

Molecular Cell
Bertrand Llorente, Mauro Modesti

Abstract

In this issue of Molecular Cell, Mazloum and Holloman (2009b) propose that 5' end strand invasion promoted by collaboration between Rad51 and Brh2 could be used for bypassing lesions during DNA replication, potentially advancing understanding of BRCA2 tumor suppressor function.

References

Dec 11, 2007·Oncogene·T Thorslund, S C West
May 29, 2009·DNA Repair·Eleni P Mimitou, Lorraine S Symington

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Citations

Jul 7, 2011·FEMS Microbiology Reviews·Evelyn VollmeisterMichael Feldbrügge

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