PMID: 11607502Dec 20, 1994Paper

Fungal degradation of recalcitrant nonphenolic lignin structures without lignin peroxidase

Proceedings of the National Academy of Sciences of the United States of America
E SrebotnikK E Hammel

Abstract

Lignin peroxidases (LiPs) are likely catalysts of ligninolysis in many white-rot fungi, because they have the unusual ability to depolymerize the major, recalcitrant, non-phenolic structures of lignin. Some white-rot fungi have been reported to lack LiP when grown on defined medium, but it is not clear whether they exhibit full ligninolytic competence under these conditions. To address this problem, we compared the abilities of a known LiP producer, Phanerochaete chrysosporium, with those of a reported nonproducer, Ceriporiopsis subvermispora, to degrade a synthetic lignin with normal phenolic content, a lignin with all phenolic units blocked, and a dimer, 1-(4-ethoxy-3-methoxyphenyl)-2-(2-methoxyphenoxy)propane-1,3-diol, that represents the major nonphenolic structure in lignin. P. chrysosporium mineralized all three models rapidly in defined medium, but C. subvermispora showed appreciable activity only toward the more labile phenolic compound under these conditions. However, in wood, its natural environment, C. subvermispora mineralized all of the models as rapidly as P. chrysosporium did. Defined media therefore fail to elicit a key component of the ligninolytic system in C. subvermispora. A double-labeling experiment with t...Continue Reading

References

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Apr 15, 1991·Biochemical and Biophysical Research Communications·H WariishiM H Gold
Jun 1, 1986·Proceedings of the National Academy of Sciences of the United States of America·K E HammelT K Kirk
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Citations

Jan 15, 2011·Applied Biochemistry and Biotechnology·Zhi-Min LiShu-lin Chen
Mar 14, 1997·Journal of Biotechnology·P Ander, L Marzullo
Aug 16, 2003·European Journal of Biochemistry·Francesca d'Acunzo, Carlo Galli
Jan 7, 2015·Biotechnology Advances·Line MunkAnne S Meyer
Aug 8, 2013·Mycologia·Francisco J Ruiz-DueñasAngel T Martínez
Feb 1, 1997·Applied Biochemistry and Biotechnology·A Sarikaya, M R Ladisch
Feb 23, 2008·Organic & Biomolecular Chemistry·Mahelet Aweke TadesseFederica Sergi
Feb 2, 2000·Applied and Environmental Microbiology·C Johannes, A Majcherczyk
Mar 23, 2012·The Journal of Biological Chemistry·Elena Fernández-FueyoAngel T Martínez
Aug 22, 2017·Analytical Biochemistry·Jeffrey D GobyChristine J Kelly
Sep 1, 1995·Applied and Environmental Microbiology·S KawaiK E Hammel
Mar 15, 2006·Applied and Environmental Microbiology·P J Collins, A Dobson

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