Fungal infections after haematology unit renovation: evidence of clinical, environmental and economical impact

European Journal of Haematology
Ricardo AraujoJose Eduardo Guimaraes

Abstract

The Haemato-Oncology Unit, Hospital S. Joao, suffered extensive refurbishing intervention in order to adapt for autotransplant patients. Eight new individual rooms with central HEPA filtration system were built. All patients admitted in the department during 14 months prior to and 14 months after renovation works were enrolled. A total of 403 admissions were considered and a detailed analysis of all patients with fungal infections, air quality and antifungal consumption were evaluated in order to study clinical, environmental and economical impact after unit renovation. Patients with acute myeloid leukaemia submitted to induction treatment were the most susceptible to acquisition of fungal infections. Fungal infections were reduced after installation of HEPA filters in individual rooms, particularly proven and probable fungal infections. No patients were diagnosed with proven or probable mould infection in the period after the unit renovation and no deaths were registered among patients with the diagnosis of possible fungal infection. Considering the group of patients diagnosed with fungal infection, the average of hospitalization was reduced 3 d in the latter period. The new high-protected rooms showed a reduction of 50% and 9...Continue Reading

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Citations

Aug 21, 2012·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·F Beirão, R Araujo
Jun 27, 2014·Medical Mycology·Guillaume DesoubeauxLouis Bernard
Jul 21, 2015·Environmental Microbiology Reports·Joana TeixeiraRicardo Araujo
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Feb 9, 2010·Medical Mycology·Ricardo AraujoLeonor Gusmão
Aug 28, 2020·Environmental Science & Technology·Ehsan S MousaviJodi D Sherman

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