Fungal keratitis in the Republic of Ireland

Eye
S FarrellC C Murphy

Abstract

PurposeFungal keratitis is relatively rare in temperate climates with only one previous population-based study, which reported a minimum annual incidence of 0.32 per million population in the United Kingdom. We performed a nationwide study in the Republic of Ireland of cases over a 6-year period to establish the incidence, risk factors, treatment, and outcomes of fungal keratitis.Patients and methodsAll corneal scraping specimens positive for fungal species over a 6-year period were identified at the microbiology departments of the seven main ophthalmology units in the Republic of Ireland. Census data was used to establish national minimum annual incidence.ResultsForty-two eyes were treated for confirmed fungal keratitis during the 6-year period. This resulted in a minimum incidence of 1.53 cases per million population per year. Twenty-eight of 42 cases (67%) were due to filamentary fungi, with the most common species being Aspergillus. Pre-existing ocular surface disease was the most common risk factor constituting 42.9%; 26.2% underwent keratoplasty. No eyes underwent evisceration. Two eyes resulted in a level of vision of no perception of light. The mean LogMAR acuity in the remainder of cases was 0.89 with a range from -0.1...Continue Reading

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Citations

Jan 27, 2018·Journal of Fungi·Felix BongominDavid W Denning
Feb 28, 2019·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·M RothG Geerling
Aug 29, 2020·Translational Vision Science & Technology·Ning HungChing-Hsi Hsiao
Jul 28, 2019·International Journal of Molecular Sciences·Ming-Tse KuoHuey-Ling You
Aug 12, 2020·Vestnik oftalmologii·N I Davletshina, A N Samoylov
Jul 25, 2019·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·Ghada Ibrahim Ibrahim BarakatAmira Mohammed Sultan
Jan 12, 2021·Frontiers in Bioengineering and Biotechnology·Benedikt GöttelKarsten Mäder
Nov 20, 2020·Clinical Ophthalmology·Ana Maria CunhaJoão Pinheiro-Costa
Mar 6, 2021·Medical Mycology Case Reports·Alexander M AldejohannDaniel Kampik

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