Fungal Nanophase Particles Catalyze Iron Transformation for Oxidative Stress Removal and Iron Acquisition.

Current Biology : CB
Guang-Hui YuGeoffrey Michael Gadd

Abstract

Microbe-mineral interactions have shaped the surface of the Earth and impacted the evolution of plants and animals. Although more than two-thirds of known mineral species have biological imprints, how the biotransformation of minerals may have benefited microbial development, beyond nutritional and energetic use, remains enigmatic. In this research, we have shown that biogenic ferrihydrite nanoparticles are extensively formed at the interface between an actively growing fungus and an iron-containing mineral, hematite. These biogenic nanoparticles formed through the fungus-hematite interactions can behave as mimetic catalysts, similar to nanozymes that imitate peroxidase, which scavenges hydrogen peroxide for the mitigation of potential cytotoxicity. Evidence from various X-ray spectroscopic analyses indicated that non-lattice oxygen in the nanomaterials was chiefly responsible for this catalytic activity, rather than through the conventional mechanisms of iron redox chemistry. Cryo-scanning electron microscopy, high-resolution (∼30 nm) 3D volume rendering, and biomass analyses further confirmed that the organism was active and capable of mediating the catalytic reactions. We therefore hypothesize that this confers an advantage ...Continue Reading

References

Jan 1, 1988·Comparative Biochemistry and Physiology. A, Comparative Physiology·Y AoyagiT Muramatsu
May 26, 2001·Applied and Environmental Microbiology·K A JensenK E Hammel
Sep 2, 2004·Biomedical Chromatography : BMC·Li LinxiangNaoki Miyata
Jun 22, 2005·Journal of Synchrotron Radiation·B Ravel, M Newville
Dec 16, 2005·The Journal of Experimental Biology·Douglas A Pace, Donal T Manahan
May 26, 2007·Science·F Marc MichelJohn B Parise
Mar 22, 2008·Science·Michael F HochellaBenjamin S Twining
Mar 22, 2008·Science·Alexandra NavrotskyJuraj Majzlan
Apr 19, 2008·Nature Chemical Biology·Christine C Winterbourn
Jul 26, 2008·Nature Nanotechnology·Lizeng GaoXiyun Yan
Feb 6, 2009·Environmental Science & Technology·Ryan C HunterTerry J Beveridge
Nov 26, 2009·Critical Reviews in Biotechnology·Hassan KorbekandiSajjad Abbasi
Dec 15, 2010·Journal of the American Chemical Society·Maxim A VoinovAlex I Smirnov
Jul 18, 2012·Proceedings of the National Academy of Sciences of the United States of America·Colleen M HanselSamuel M Webb
Oct 25, 2012·Journal of Synchrotron Radiation·Qingxi YuanZiyu Wu
Aug 28, 2013·Proceedings of the National Academy of Sciences of the United States of America·Jens BaumgartnerDamien Faivre
Oct 21, 2014·Nature Reviews. Microbiology·Emily D MeltonAndreas Kappler
Jan 9, 2015·Environmental Science & Technology·Daniela MedasPierfranco Lattanzi
Apr 13, 2017·Environmental Science & Technology·Guanghui YuQirong Shen
Jan 25, 2018·Journal of the American Chemical Society·Kelsey K SakimotoPeidong Yang
Apr 26, 2018·Journal of Physics. Condensed Matter : an Institute of Physics Journal·Jack StrandAlexander L Shluger
Jun 8, 2018·FEMS Microbiology Ecology·Laura NewsomeJonathan R Lloyd
Sep 1, 2006·Medical Mycology·Jesús AguirreRosa Navarro
May 24, 2019·Nature·Corentin C LoronEmmanuelle J Javaux

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.