Oct 15, 1989

Further characterization of sulfated homopolysaccharides as anti-HIV agents

Experientia
I SugawaraK Shimada

Abstract

Fucoidan and dextran sulfate showed anti-HIV activities against mononuclear cells from AIDS patients, and they abrogated HIV reverse transcriptase (RT) activity by interacting with the HIV envelope in the membranes of target cells. Furthermore, they showed a synergistic effect with azidothymidine (AZT).

Mentioned in this Paper

Retrovir
Dextran Sulfate
Mononuclear Cells
Tissue Membrane
Zidovudine
HIV Reverse Transcriptase
Dextran Sulfate Sodium
Fucoidan
Reverse Transcriptase Inhibitors
Anti-HIV Agents

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