PMID: 16615662Apr 18, 2006Paper

Further evidence of the usefulness of Acute Physiology and Chronic Health Evaluation II scoring system in acute paraquat poisoning

Clinical Toxicology : the Official Journal of the American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists
Neng Chyan HuangJeng-Hsien Yeh

Abstract

We have previously successfully applied the Acute Physiology and Chronic Health Evaluation (APACHE) II system to assess the severity of patients with acute paraquat poisoning, and this article investigates further evidence of the usefulness of APACHE II system in predicting the in-hospital mortality of 64 patients with acute paraquat poisoning over a period of 12 years. The predictive factors including APACHE II score, plasma paraquat concentration, severity index of paraquat poisoning (SIPP), and estimated ingestion dosage of paraquat for evaluating the outcome in paraquat-poisoned patients were assessed. Overall mortality was 71.9%: 46 out of 64 patients died. Non-survivors (n = 46) had a higher APACHE II score (23.3 +/- 12.7) than survivors (n = 18) (6.1 +/- 4.2) (p < 0.001). The plasma paraquat concentration, SIPP, and estimated ingestion dosage of paraquat were significantly higher in non-survivors than in survivors (p < 0.05, in all comparisons). By multiple logistic regression analysis, only the APACHE II score and peak data of blood sugar in 24 h after admission were capable of predicting in-hospital mortality. By using the area under receiver operating characteristic curves (AURC), the APACHE II system yielded better d...Continue Reading

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Citations

Nov 15, 2011·Clinical Toxicology : the Official Journal of the American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists·Young-Gi MinChi Keung Chan
Dec 20, 2011·Clinical Toxicology : the Official Journal of the American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists·Younghwan LeeSeong Youn Hwang
Oct 6, 2011·Clinical Toxicology : the Official Journal of the American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists·Changbao Huang, Xigang Zhang
Jun 17, 2008·The American Journal of the Medical Sciences·Meng-Wei ChangYui-Rwei Young
Apr 25, 2009·Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine·Jaiyong KimKyoung Jun Song
Jul 26, 2014·The Journal of Emergency Medicine·Chih-Chuan LinKuang-Hung Hsu
Sep 21, 2016·Clinical Toxicology : the Official Journal of the American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists·Raya BrandenburgDylan W de Lange
Nov 9, 2016·Scientific Reports·Deng-Chuan ZhouCheng-Fan Zhou
Dec 29, 2007·Critical Reviews in Toxicology·R J Dinis-OliveiraF Carvalho
Jan 24, 2018·Journal of Intensive Care Medicine·Shannon M FernandoKwadwo Kyeremanteng
Jul 16, 2019·The Journal of International Medical Research·Yue SongYuhong Tao
Mar 12, 2017·Journal of Medical Toxicology : Official Journal of the American College of Medical Toxicology·Evan S SchwarzJeffrey Brent
Apr 23, 2016·Medical Science Monitor : International Medical Journal of Experimental and Clinical Research·Shuai LiuAi Peng
Aug 4, 2021·The American Journal of Emergency Medicine·Sung Jin KimJong-Hak Park

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