Further evidence that culture media affect perinatal outcome: findings after transfer of fresh and cryopreserved embryos

Human Reproduction
Ewka C M NelissenJohn C M Dumoulin

Abstract

We have previously shown that the medium used for culturing IVF embryos affects the birthweight of the resulting newborns. This observation with potentially far-reaching clinical consequences during later life, was made in singletons conceived during the first IVF treatment cycle after the transfer of fresh embryos. In the present study, we hypothesize that in vitro culture of embryos during the first few days of preimplantation development affects perinatal outcome, not only in singletons conceived in all rank order cycles but also in twins and in children born after transfer of frozen embryos. Furthermore, we investigated the effect of culture medium on gestational age (GA) at birth. Oocytes and embryos from consecutive treatment cycles were alternately assigned to culture in either medium from Vitrolife or from Cook. Data on a cohort of 294 live born singletons conceived after fresh transfer during any of a patient's IVF treatment cycles, as well as data of 67 singletons conceived after frozen embryo transfer (FET) and of 88 children of 44 twin pregnancies after fresh transfer were analysed by means of multiple linear regression. In vitro culture in medium from Cook resulted in singletons after fresh transfer with a lower me...Continue Reading

References

Aug 12, 1978·Lancet·P C Steptoe, R G Edwards
Aug 1, 1984·Fertility and Sterility·G H ZeilmakerA C Drogendijk
Jan 1, 1996·British Journal of Obstetrics and Gynaecology·H Rydhstroem
Sep 19, 2002·Molecular Reproduction and Development·Marcelo BertoliniGary B Anderson
Jan 6, 2004·Obstetrics and Gynecology·Rebecca C AmaruSreedhar Gaddipati
Feb 18, 2004·Twin Research : the Official Journal of the International Society for Twin Studies·Isaac Blickstein, Robin B Kalish
Mar 3, 2004·Obstetrics and Gynecology·Rebecca A JacksonMary S Croughan
Jul 9, 2004·Development·Mellissa R W MannMarisa S Bartolomei
Aug 31, 2004·Reproduction : the Official Journal of the Society for the Study of Fertility·Paolo Rinaudo, Richard M Schultz
Nov 30, 2004·Human Reproduction·Michèle HansenJennifer J Kurinczuk
Dec 14, 2004·Human Reproduction·John C M DumoulinEdith Coonen
Jan 11, 2005·Journal of the American College of Nutrition·D J P Barker
Feb 12, 2005·Journal of Assisted Reproduction and Genetics·Alfred A RimmK Paul Katayama
Mar 5, 2005·American Journal of Obstetrics and Gynecology·Israel HendlerYoram Sorokin
Apr 22, 2005·BJOG : an International Journal of Obstetrics and Gynaecology·Fiona ThomsonSiladitya Bhattacharya
Jul 11, 2006·Human Reproduction·Jolande A Land
Nov 9, 2006·Best Practice & Research. Clinical Obstetrics & Gynaecology·Michelle Lane, David K Gardner
Jun 9, 2007·Fetal Diagnosis and Therapy·Shunji Suzuki, Tomoaki Murata
Jan 1, 2008·Obstetrics and Gynecology·Donald D McIntire, Kenneth J Leveno
Mar 28, 2008·JAMA : the Journal of the American Medical Association·Geeta K SwamyRolv Skjaerven
Jun 27, 2008·The Journal of Reproduction and Development·Shu HashimotoYoshiharu Morimoto
Oct 14, 2008·Fertility and Sterility·John D Biggers, Michael C Summers
Jul 7, 2009·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Sarah D McDonaldUNKNOWN Knowledge Synthesis Group
Oct 17, 2009·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Sarah D McDonaldUNKNOWN Knowledge Synthesis Group
Jan 21, 2010·Human Reproduction·John C DumoulinJohannes L Evers
Feb 27, 2010·BJOG : an International Journal of Obstetrics and Gynaecology·B KällénP Otterblad Olausson
Jun 24, 2010·Human Reproduction·J de MouzonUNKNOWN European IVF-monitoring (EIM) Consortium, for the European Society of Human Reproduction and Embryology (ESHRE)
Jul 22, 2010·BMJ : British Medical Journal·Sarah D McDonaldUNKNOWN Knowledge Synthesis Group

❮ Previous
Next ❯

Citations

Sep 21, 2013·Journal of Assisted Reproduction and Genetics·Michael C Summers
Oct 23, 2013·Reproductive Biomedicine Online·Daniel R BrisonSusan J Kimber
Dec 13, 2012·Human Reproduction·S MäkinenT Tuuri
Apr 19, 2013·Human Reproduction·Shengli LinPing Liu
Feb 7, 2013·Human Reproduction Update·E MantikouS Mastenbroek
Dec 25, 2012·Molecular Human Reproduction·S K FeuerP F Rinaudo
Aug 7, 2012·The Journal of Clinical Endocrinology and Metabolism·Elena LabartaAntonio Pellicer
Feb 20, 2014·Human Reproduction·Sander H M KleijkersJohn C M Dumoulin
Dec 11, 2013·Human Reproduction·Sandra A HemkemeyerVerena Nordhoff
Jan 11, 2014·Human Reproduction·Jinliang ZhuJie Qiao
Apr 5, 2014·Molecular Human Reproduction·C De PaepeH Van de Velde
May 21, 2014·Seminars in Fetal & Neonatal Medicine·Anna-Karina Aaris Henningsen, Anja Pinborg
Jul 19, 2014·Human Reproduction Update·Elpiniki Chronopoulou, Joyce C Harper
Aug 15, 2014·Human Fertility : Journal of the British Fertility Society·Virginia N BoltonDaniel R Brison
Sep 18, 2013·Reproductive Biomedicine Online·Jacques Cohen, Mina Alikani
Aug 7, 2013·Fertility and Sterility·Beatriz CarrascoAnna Veiga
Aug 3, 2013·Fertility and Sterility·Arne Sunde, Basak Balaban
Apr 23, 2013·Fertility and Sterility·Phoebe H LeonardDean E Morbeck
Feb 5, 2013·Fertility and Sterility·Laxmi A Kondapalli, Alfredo Perales-Puchalt
Jan 15, 2013·Fertility and Sterility·Edwina H Yeung, Charlotte Druschel
Dec 17, 2015·Journal of Huazhong University of Science and Technology. Medical Sciences = Hua Zhong Ke Ji Da Xue Xue Bao. Yi Xue Ying De Wen Ban = Huazhong Keji Daxue Xuebao. Yixue Yingdewen Ban·Tai-Lang YinJing Yang
Jan 15, 2014·BJOG : an International Journal of Obstetrics and Gynaecology·K V NaverL Nilas
Dec 3, 2014·Reproductive Biomedicine Online·Shengli LinJie Qiao
Apr 14, 2016·Theriogenology·Huanhuan ChenYong Zhang
May 24, 2013·Biochemical Society Transactions·Kirsten R McEwenPetra Hajkova
May 27, 2015·Theriogenology·R LavaraJ S Vicente
Jun 19, 2014·Human Fertility : Journal of the British Fertility Society·Michael C Summers
Apr 11, 2015·Human Reproduction·Sander H M KleijkersJohn C M Dumoulin

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.