Further insight on A-wave in acute and chronic demyelinating neuropathies

Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
Ferdinando SartucciAlessandro Rossi


A-wave is a late motor response that maintains the same characteristics of latency, amplitude and shape with every electrical stimuli at a proper given intensity. The presence of A-waves was reported both in chronic (CIDP) and acute (AIDP) forms of inflammatory demyelinating polyradiculoneuropathy. It is attributed to the effect of either sprouting phenomena or ephaptic/ectopic discharge. In the first condition it could be a sign of functional recovery, while in the second it could represent an early indicator of demyelination. Aims of our research were to investigate retrospectively the presence of the A-waves, establishing whether its frequency is more common in CIDP or AIDP. Data from 77 patients, 57 male and 20 female, mean age 60.7 years (SD 15.4), were recovered from clinical records and their neurophysiological tests retrieved for reanalysis. Our results seem to indicate that A-waves can represent an early sign of acute pathology of peripheral nervous system.


Jul 1, 1979·Neurology·Z Seltzer, M Devor
Apr 1, 1992·Electroencephalography and Clinical Neurophysiology·M R Magistris, G Roth
Jan 1, 1990·Annals of Neurology·A K Asbury, D R Cornblath
Aug 1, 1993·Electroencephalography and Clinical Neurophysiology·G Roth
Dec 1, 1996·Electroencephalography and Clinical Neurophysiology·C BischoffL Puksa
Mar 23, 1999·Muscle & Nerve·M E KornhuberB Conrad
May 20, 2000·Acta Neurologica Scandinavica. Supplementum·N Attal, D Bouhassira
Jul 7, 2000·Muscle & Nerve·J Rowin, M N Meriggioli
May 16, 2001·Muscle & Nerve·D S SapersteinR J Barohn
Jun 19, 2001·Archives of Neurology·P H Gordon, A J Wilbourn
Jul 13, 2002·Muscle & Nerve. Supplement·Christian Bischoff
Apr 23, 2003·Neurology·Howard W Sander, Norman Latov
Jan 1, 1955·Brain : a Journal of Neurology·G CAUSEY, H HOFFMAN
Feb 1, 1965·Journal of Neurology, Neurosurgery, and Psychiatry·P M FULLERTON, R W GILLIATT
Oct 23, 2003·Muscle & Nerve·Leena PuksaBjörn Falck
Mar 31, 2004·Muscle & Nerve·Peter Y K Van den Bergh, Françoise Piéret
Aug 4, 2004·Brain : a Journal of Neurology·K VialaP Bouche
May 10, 2005·Muscle & Nerve·Amer Al-ShekhleeBashar Katirji
May 24, 2005·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Hatice TankisiUNKNOWN Esteem Project
Oct 14, 2005·Journal of the Peripheral Nervous System : JPNS·Yusuf A RajaballyMajed Hbahbih
Apr 21, 2006·Journal of Neurology, Neurosurgery, and Psychiatry·A CaselliL Uccioli
Jul 25, 2006·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Yusuf A Rajabally, Saiju Jacob
Nov 11, 2006·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Steve VucicDidier Cros
Feb 28, 2007·Neurologic Clinics·Richard A Lewis
Apr 11, 2008·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Grégory BarrièreSerge Rossignol
Jan 9, 2009·Clinical Pharmacology and Therapeutics·J R Senior
Jan 27, 2009·Journal of Clinical Neuromuscular Disease·Deepak GuptaUNKNOWN Diplomate-American Board

❮ Previous
Next ❯


May 31, 2018·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·Sindhuja LakshminarasimhanLakshminarasimhan Ranganathan
Jun 3, 2011·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·José A GarbinoPedro Schestatsky
Aug 19, 2020·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Liborio RampelloFrancesco Patti

❮ Previous
Next ❯

Related Concepts

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.


Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.


Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.