PMID: 591983Dec 1, 1977

Further motor unit studies in Duchenne muscular dystrophy

Journal of Neurology, Neurosurgery, and Psychiatry
A J McComasM E Brandstater

Abstract

Numbers of functioning motor units have been estimated in 124 muscles of boys with Duchenne dystrophy; some of the patients were studied on several occasions. In the distal muscles examined (extensor digitorum brevis, thenar, and hypothenar muscles) the losses of units were probably present at birth and did not decrease with age. In contrast, the numbers of units and of excitable muscle fibres in the soleus muscles declined significantly, especially between the ages of 9 and 12 years.

References

Jan 1, 1974·Journal of Neurology, Neurosurgery, and Psychiatry·R E SicaD Longmire
Aug 1, 1974·Journal of Neurology, Neurosurgery, and Psychiatry·J P Ballantyne, S Hansen
Sep 1, 1974·Journal of the Neurological Sciences·C P PanayiotopoulosT Papapetropoulos
Aug 1, 1971·Journal of Neurology, Neurosurgery, and Psychiatry·A J McComasS Currie
Jun 27, 1970·Nature·A J Mc ComasS Currie
Apr 1, 1971·Journal of Neurology, Neurosurgery, and Psychiatry·A J McComasR E Sica

Citations

Jan 1, 1988·Progress in Neurobiology·A J McComasS Garner
May 30, 2001·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·J M Shefner
Jun 11, 2003·Physical Medicine and Rehabilitation Clinics of North America·J M Shefner, Clifton L Gooch
Jan 1, 1997·Muscle & Nerve·M SlawnychC Hershler
May 1, 1978·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·R E Sica, A J McComas
Mar 17, 2019·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Ali Amin LariHamid Reza Bokaee

Related Concepts

Ankle
Potentials, Event-Related
Hand
Muscle
Muscular Dystrophy
Nerve-Muscle Preparation
Toes

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Alzheimer's Disease: MS4A

Variants within the membrane-spanning 4-domains subfamily A (MS4A) gene cluster have recently been implicated in Alzheimer's disease in genome-wide association studies. Here is the latest research on Alzheimer's disease and MS4A.

Pediculosis pubis

Pediculosis pubis is a disease caused by a parasitic insect known as Pthirus pubis, which infests human pubic hair, as well as other areas with hair including eye lashes. Here is the latest research.

Rh Isoimmunization

Rh isoimmunization is a potentially preventable condition that occasionally is associated with significant perinatal morbidity or mortality. Discover the latest research on Rh Isoimmunization here.

Genetic Screens in iPSC-derived Brain Cells

Genetic screening is a critical tool that can be employed to define and understand gene function and interaction. This feed focuses on genetic screens conducted using induced pluripotent stem cell (iPSC)-derived brain cells. It also follows CRISPR-Cas9 approaches to generating genetic mutants as a means of understanding the effect of genetics on phenotype.

Enzyme Evolution

This feed focuses on molecular models of enzyme evolution and new approaches (such as adaptive laboratory evolution) to metabolic engineering of microorganisms. Here is the latest research.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Pharmacology of Proteinopathies

This feed focuses on the pharmacology of proteinopathies - diseases in which proteins abnormally aggregate (i.e. Alzheimer’s, Parkinson’s, etc.). Discover the latest research in this field with this feed.

Alignment-free Sequence Analysis Tools

Alignment-free sequence analyses have been applied to problems ranging from whole-genome phylogeny to the classification of protein families, identification of horizontally transferred genes, and detection of recombined sequences. Here is the latest research.