PMID: 38346Sep 1, 1979

Further observation on the denervation supersensitivity of the urethra in patients with chronic neurogenic bladders

The Journal of Urology
T Koyanagi


The response of the urethra in patients with chronic neurogenic bladders to autonomic stimulation was investigated by urethral pressure profile. A consistent supersensitivity to alpha-adrenergic stimulation was documented. Experiments with various autonomic blocking drugs confirmed that this response is alpha-adrenergically mediated via the short neuron system. The results appear to offer pharmacological evidence for the recently evolving intricate innervation pattern of the urethra including its distal portion, where the alpha-adrenergic system is believed to be important.


Jan 1, 1977·Urologia Internationalis·T Koyanagi, I Tsuji
Apr 1, 1977·Urology·A E FinkbeinerL Welch
Oct 1, 1975·Nihon Hinyōkika Gakkai zasshi. The japanese journal of urology·T Koyanagi
Jun 1, 1972·The Journal of Urology·J E McNeal
Dec 1, 1973·The Journal of Urology·R J Krane, C A Olsson


May 1, 1997·International Journal of Urology : Official Journal of the Japanese Urological Association·N SekidoH Akaza
Oct 1, 1985·Acta Pharmacologica Et Toxicologica·J Ekström, L Malmberg

Related Concepts

Adrenergic Agonists
Autonomic Nervous System
Neurogenic Urinary Bladder, Uninhibited
Ganglionic Blockers
Neural Pathways
Antispasmodic Effect
Parasympathomimetic Effect
Urethral Sphincters

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