PMID: 9543727Apr 17, 1998Paper

Further studies on analgesic activity of cyclic imides

Il Farmaco
V Cechinel FilhoRosendo Augusto Yunes

Abstract

As part of our research programme to obtain pharmacologically active compounds structurally related to cyclic imides, we have synthesized different compounds and examined their analgesic activities using the abdominal constriction test in mice. The results showed that some of the compounds studied, given intraperitoneally, exhibited graded and significant analgesia against acetic acid-induced abdominal constriction, being several times more potent than aspirin and paracetamol, two standard drugs used for comparison.

References

May 1, 1988·Journal of Natural Products·M S TempestaJ B Calixto
Feb 1, 1968·British Journal of Pharmacology and Chemotherapy·H O CollierC Schneider

❮ Previous
Next ❯

Citations

Jan 1, 2009·Acta Crystallographica. Section E, Structure Reports Online·A ChitradeviS Asath Bahadur
Jan 1, 2010·Acta Crystallographica. Section E, Structure Reports Online·Hoong-Kun FunSalman A Khan
Aug 13, 2011·Acta Crystallographica. Section E, Structure Reports Online·Hualing ZhuWei Xu
Dec 27, 2012·Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy·A Z El-SonbatiH A Seyam
Feb 8, 2008·European Journal of Medicinal Chemistry·Samir BondockAhmed A Fadda
Sep 9, 2015·Organic Letters·Veeranjaneyulu LankeKandikere Ramaiah Prabhu
Oct 1, 2011·Saudi Pharmaceutical Journal : SPJ : the Official Publication of the Saudi Pharmaceutical Society·Rishikesh V AntreRajesh J Oswal
Aug 11, 2016·Chemico-biological Interactions·Daiane RosolenTânia Beatriz Creczynski-Pasa
Aug 17, 2010·European Journal of Medicinal Chemistry·Fernanda MahleFátima de Campos-Buzzi

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.