PMID: 8591832Nov 30, 1995Paper

Further validation of a quadruplex STR DNA typing system: a collaborative effort to identify victims of a mass disaster

Forensic Science International : Synergy
T M ClaytonP Gill

Abstract

The relatively new, PCR-based technique of Short Tandem Repeat (STR) profiling has been used in the identification of the victims of a mass disaster. The analysis relied upon a recently developed multiplex reaction and the use of automated fluorescence technology to simulataneously analyse four tetrameric STR loci. The performance of the 'quadruplex' test was assessed by use of a collaborative study incorporating a blind trial and was demonstrated to be accurate, reliable and robust. Furthermore, the system proved to be highly successful despite the fact that many of the samples from the mass disaster scene were extremely degraded. The high success rate coupled with the discrimination power of the system enabled many severely decomposed human remains to be positively identified.

References

Sep 1, 1992·Forensic Science International : Synergy·A J JeffreysA Sonnberg
Oct 11, 1992·Nucleic Acids Research·P S WalshR Reynolds
Aug 1, 1992·PCR Methods and Applications·K M SullivanJ M Robertson
Apr 1, 1992·Genomics·J S Beckman, J L Weber
Jan 1, 1994·International Journal of Legal Medicine·J E LygoP Gill
Feb 1, 1994·Nature Genetics·P GillK Sullivan
Aug 1, 1993·PCR Methods and Applications·C P KimptonM Adams

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Citations

Sep 1, 2006·Forensic Science, Medicine, and Pathology·Eleanor A M Graham
Nov 26, 2014·International Journal of Legal Medicine·Muhammad ShafiqueTayyab Husnain
Oct 9, 2012·Forensic Science International. Genetics·Teri KunElizabeth J Wictum
Jun 19, 2010·Forensic Science International : Synergy·Vilma PinchiGian-Aristide Norelli
Jul 14, 1998·The American Journal of Forensic Medicine and Pathology·R Fernando, P Vanezis
Jun 15, 1997·Analytical Chemistry·T A Brettell, R Saferstein

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