Fusidic acid-resistant Staphylococcus aureus in impetigo contagiosa and secondarily infected atopic dermatitis

Acta Dermato-venereologica
Mikael AlsterholmJan Faergemann

Abstract

Fusidic acid-resistant Staphylococcus aureus (FRSA) has been identified as a causative agent in outbreaks of impetigo and its emergence has been associated with increased use of topical fusidic acid. The frequency of FRSA in atopic dermatitis (AD) has been less extensively investigated. The aim of this study was to investigate the bacterial spectrum and frequency of FRSA in patients with impetigo or secondarily infected AD. A prospective study in our clinic in 2004 to 2008 included 38 patients with impetigo and 37 with secondarily infected AD. S. aureus was the predominant finding in all groups (bullous impetigo 92% (12/13), impetigo 76% (19/25) and secondarily infected AD 89% (33/37)). Seventy-five percent of S. aureus were fusidic acid resistant in bullous impetigo, 32% in impetigo and 6.1% in secondarily infected AD (bullous impetigo vs. AD p < 0.0001, impetigo vs. AD p < 0.05). We then performed a retrospective patient record review including all patients with impetigo or secondarily infected AD seen at the clinic during the first and last year of the prospective study. In the first year 33% (19/58) of the S. aureus isolates were fusidic acid-resistant in impetigo and 12% (5/43) in secondarily infected AD (p < 0.05). In the...Continue Reading

Citations

Mar 12, 2011·The Journal of Antimicrobial Chemotherapy·Sverre RørtveitGuri Rortveit
Dec 30, 2015·Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG·Thomas WerfelUNKNOWN Association of Scientific Medical Societies of Germany
Nov 26, 2010·Dermatologic Clinics·Steven Y C TongJonathan R Carapetis
Oct 27, 2011·Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG·Helmut SchöferUNKNOWN Paul Ehrlich Society for Chemotherapy (PEG)
May 10, 2012·Expert Opinion on Pharmacotherapy·Gérald E PiérardClaudine Piérard-Franchimont
Mar 19, 2015·Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete·M Mempel, C Schnopp
Nov 10, 2016·Anais Brasileiros De Dermatologia·Giancarlo Rezende BessaPedro Alves D'Azevedo
Jan 20, 2012·The Cochrane Database of Systematic Reviews·Sander KoningJohannes C van der Wouden
Jan 29, 2019·Expert Review of Anti-infective Therapy·Jordi VilaRafael Cantón
May 28, 2019·Future Microbiology·Ian MorrisseyYuly López
Aug 9, 2019·Expert Review of Anti-infective Therapy·Philip NikolicJohn Whitehall
Apr 13, 2019·Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete·Luisa Hellmich, Mario Fabri
May 10, 2020·MicrobiologyOpen·Philip NikolicJohn Whitehall
May 11, 2018·Future Microbiology·Rafael CantonCristina Tarragó
Oct 10, 2012·Anais Brasileiros De Dermatologia·Vanessa PetryPedro Alves d'Azevedo
May 3, 2021·Antimicrobial Resistance and Infection Control·Bahareh HajikhaniMasoud Dadashi
Jan 21, 2020·Dermatology : International Journal for Clinical and Investigative Dermatology·Antonio TorreloIlonka Zsolt

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