Future of evidence ecosystem series: 2. current opportunities and need for better tools and methods.

Journal of Clinical Epidemiology
Perrine CréquitPhilippe Ravaud

Abstract

To become user driven and more useful for decision-making, the current evidence synthesis ecosystem requires significant changes (Paper 1. Future of evidence ecosystem series). Reviewers have access to new sources of data (clinical trial registries, protocols, and clinical study reports from regulatory agencies or pharmaceutical companies) for more information on randomized control trials. With all these newly available data, the management of multiple and scattered trial reports is even more challenging. New types of data are also becoming available: individual patient data and routinely collected data. With the increasing number of diverse sources to be searched and the amount of data to be extracted, the process needs to be rethought. New approaches and tools, such as automation technologies and crowdsourcing, should help accelerate the process. The implementation of these new approaches and methods requires a substantial rethinking and redesign of the current evidence synthesis ecosystem. The concept of a "living" evidence synthesis enterprise, with living systematic review and living network meta-analysis, has recently emerged. Such an evidence synthesis ecosystem implies conceptualizing evidence synthesis as a continuous ...Continue Reading

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Citations

Sep 16, 2020·Annals of Internal Medicine·Isabelle BoutronUNKNOWN COVID-NMA Consortium
Dec 18, 2020·Journal of Clinical Epidemiology·Kristina LindsleyLotty Hooft
Mar 8, 2020·Journal of Clinical Epidemiology·Isabelle BoutronPhilippe Ravaud

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