Future perspectives in Orbitrap™-high-resolution mass spectrometry in food analysis: a review

Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment
Hamide Z SenyuvaEbru Ates Sarikaya

Abstract

A literature search from 2007 to 2014 was conducted to identify publications where principally LC-Orbitrap™-high-resolution mass spectrometry (HRMS) has been employed in food analysis. Of a total of 212 relevant references, only 22 papers were from 2007-10, but in subsequent years there has been a steady growth in publications with 38-55 relevant papers being published each year from 2011 to 2014. In the food safety area, over 50% of the published papers were equally divided between pesticides, veterinary drug residues and natural toxins (including mycotoxins) focused primarily on multi-analyte target analysis. LC-Orbitrap-HRMS was also found to be increasingly important for the analysis of bioactive substances, principally phenolic compounds in foods. A number of studies reported for the first time the identification of new fungal metabolites, predominantly various conjugated forms of known mycotoxins. Novel process contaminants were also identified by LC-Orbitrap-HRMS, as were various substances used for food adulteration and bioactive substances in herbal products and dietary supplements. Untargeted analysis is seen as a major future trend where HRMS plays a significant role. Retrospective analysis of scanned high-resolution...Continue Reading

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Citations

Dec 15, 2015·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·Melody Yee-Man WongZhong-Ping Yao
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Jun 11, 2020·Journal of Agricultural and Food Chemistry·Yuying ZhangChanghu Xue
Sep 21, 2021·Frontiers in Genetics·Suxian YanJun Zheng

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Methods Mentioned

BETA
deamination
adsorption column chromatography
PCA
ELISA
PCR
electrophoresis
NMR
genetic modification
metabolomic profiling

Software Mentioned

DART
Exactive Plus
Web
SmartMass
MS
QuEChERS Q - [UNK] SIM
QuEChERS
ExactFinder
HRMS
MetWorks

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