Future perspectives in the treatment of cutaneous T-cell lymphoma (CTCL)

Seminars in Oncology
Reinhard Dummer

Abstract

Over the last 20 years the treatment of cutaneous T-cell lymphoma has been in a state of continual change. New therapies are constantly emerging as the search continues for more effective and tolerable disease-specific agents that satisfy medical needs. Therapies under investigation include topical retinoids, fusion molecules like denileukin diftitox, pegylated interferon, interleukin-2, and interleukin-12. Pegylated liposomal doxorubicin, gemcitabine, and chlorodeoxyadenosine also appear to have clinical potential. Other identified agents include vaccines and monoclonal antibodies. This article reviews some of the most recent clinical innovations.

References

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Citations

Feb 23, 2010·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Lluis CatasusJaime Prat
Dec 16, 2011·Journal of the European Academy of Dermatology and Venereology : JEADV·A C HüskenM Schiller
Jan 13, 2012·Cancer Biology & Therapy·Ronnie M AbrahamMariusz A Wasik
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Sep 23, 2008·The American Journal of Dermatopathology·Emma Clare BentonSean J Whittaker
Mar 28, 2007·Cancer Control : Journal of the Moffitt Cancer Center·Dorna RezaniaHernani D Cualing

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