Fuzzy Expert System based on a Novel Hybrid Stem Cell (HSC) Algorithm for Classification of Micro Array Data

Journal of Medical Systems
S Arul Antran Vijay, Pugalendhi GaneshKumar

Abstract

In the growing scenario, microarray data is extensively used since it provides a more comprehensive understanding of genetic variants among diseases. As the gene expression samples have high dimensionality it becomes tedious to analyze the samples manually. Hence an automated system is needed to analyze these samples. The fuzzy expert system offers a clear classification when compared to the machine learning and statistical methodologies. In fuzzy classification, knowledge acquisition would be a major concern. Despite several existing approaches for knowledge acquisition much effort is necessary to enhance the learning process. This paper proposes an innovative Hybrid Stem Cell (HSC) algorithm that utilizes Ant Colony optimization and Stem Cell algorithm for designing fuzzy classification system to extract the informative rules to form the membership functions from the microarray dataset. The HSC algorithm uses a novel Adaptive Stem Cell Optimization (ASCO) to improve the points of membership function and Ant Colony Optimization to produce the near optimum rule set. In order to extract the most informative genes from the large microarray dataset a method called Mutual Information is used. The performance results of the proposed...Continue Reading

References

Jan 22, 2005·Bioinformatics·Staal A VinterboLucila Ohno-Machado
Oct 23, 2009·IEEE Transactions on Information Technology in Biomedicine : a Publication of the IEEE Engineering in Medicine and Biology Society·Gerald Schaefer, Tomoharu Nakashima
May 4, 2011·Journal of Medical Systems·Hui-Ling ChenDa-You Liu
Feb 22, 2012·IEEE/ACM Transactions on Computational Biology and Bioinformatics·Cosmin LazarAnn Nowé
Feb 11, 2015·Journal of Medical Systems·D K Mak
Apr 9, 2015·Acta Diabetologica·Fulvio PomeroFrancesco Dentali
Sep 20, 2015·Journal of Medical Systems·Carmen CamaraFernando Maestú
Jul 14, 2016·IEEE Transactions on Neural Networks and Learning Systems·Xiaojun Chang, Yi Yang
Aug 9, 2016·Journal of Medical Systems·Joana DizAlberto Freitas
Jun 1, 2017·Artificial Intelligence in Medicine·Ruijie ZhangArun Kumar Sangaiah

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