G tolerance vis-à-vis pressure-distension and pressure-flow relationships of leg arteries.

European Journal of Applied Physiology
O EikenR Kölegård

Abstract

During increased gravitoinertial (G) load in the head-to-foot direction, pressures in dependent vascular beds are commonly raised to levels capable of distending precapillary vessels, which, in turn, may reduce arterial pressure, and hence compromise the capacity to withstand G load (G tolerance). We hypothesized that distensibility in precapillary leg vessels would be lower in a group of subjects possessing high G tolerance (H; n = 7; relaxed G tolerance = 6.6 ± 0.8 G) than in a group with low G tolerance (L; n = 8; G tolerance = 3.9 ± 0.3 G). The groups were matched with regard to gender, age, weight, height, and resting arterial pressure. Arterial pressure-distension and pressure-flow experiments were performed with the subject supine in a pressure chamber with a lower leg protruding to the outside. Increased intravascular pressure in the blood vessels of the outside leg was accomplished by stepwise increasing chamber pressure to 240 mmHg. Diameter and flow in the posterior tibial artery were measured by ultrasonographic/Doppler techniques. Pressure-induced increments in arterial diameter and flow were more pronounced (p < 0.03) in the L (14.1 ± 4.2% and 32 ± 21 ml/min respectively) than in the H (1.7 ± 5.0% and 1.6 ± 25 ml/...Continue Reading

References

Jul 1, 1970·Acta Physiologica Scandinavica·B FolkowL Weiss
Apr 1, 1982·American Heart Journal·A Malliani, F Lombardi
Jan 1, 1982·Medicine and Science in Sports and Exercise·G A Borg
Jul 1, 1998·Progress in Cardiovascular Diseases·C F WooleyH Boudoulas
Jul 25, 2000·Journal of Applied Physiology·N D VaziriR E Purdy
Jun 16, 2004·Acta Physiologica Scandinavica·O Eiken, R Kölegård
May 4, 2007·European Journal of Applied Physiology·N D C GreenJ H Coote
Jul 29, 2008·American Journal of Physiology. Heart and Circulatory Physiology·Ola EikenIgor B Mekjavic

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Citations

Aug 31, 2013·European Journal of Applied Physiology·Roger KölegårdOla Eiken
Aug 15, 2014·European Journal of Applied Physiology·Patrik SundbladOla Eiken
Apr 14, 2016·European Journal of Applied Physiology·Patrik SundbladOla Eiken
Nov 4, 2021·Experimental Physiology·Ross D PollockThomas G Smith

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