G2-delay after irradiation with alpha-particles as studied in synchronized cultures and by the bromodeoxyuridine-33258H technique

Cytometry
L HieberC Lücke-Huhle

Abstract

Division delay of mouse L-929 fibroblasts after alpha-irradiation is due to a pronounced lengthening of their G2-phase. Experiments on synchronously and asynchronously growing cultures revealed a cell cycle phase-dependent sensitivity of this effect: Cells irradiated in G2 or at the G1/S border suffered a longer G2-delay than cells irradiated at mid- or late-S. Progression through G2 was nearly normal at doses up to 0.3 Gy if cells were exposed during G1 phase.

References

Jan 1, 1977·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·C Lücke-Huhle, H Dertinger
Jun 13, 1975·Radiation and Environmental Biophysics·H BaischW A Linden

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Citations

Jul 1, 1994·International Journal of Radiation Biology·M ScholzG Kraft
Dec 1, 1985·International Journal of Radiation Biology and Related Studies in Physics, Chemistry, and Medicine·J Kiefer
Jan 1, 1984·Cancer Investigation·F Traganos
Jun 23, 2005·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·C Fournier, G Taucher-Scholz
Aug 18, 2009·Biochimica Et Biophysica Acta·Emmanouil FokasRita Engenhart-Cabillic
Aug 30, 2003·Oncogene·George IliakisHuichen Wang
Nov 22, 1982·Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character·E G GrayJ Barron
Jan 1, 1991·Acta Oncologica·A LaasonenL R Holsti
Jul 1, 1994·International Journal of Radiation Biology·C S GriffinJ R Savage
Jan 1, 1982·Radiation and Environmental Biophysics·C Lücke-HuhleM Pech

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