GABAergic neurons in brainstem auditory nuclei of the chick: distribution, morphology, and connectivity.

The Journal of Comparative Neurology
C S von BartheldEdwin W Rubel

Abstract

The second- and third-order auditory nuclei in the brainstem of the chicken, nucleus magnocellularis (NM) and nucleus laminaris (NL), receive afferents that are immunoreactive to gamma-aminobutyric acid (GABA). In order to investigate the source(s) of these GABAergic afferents, we examined the distribution, morphology, and connectivity of GABAergic neurons in and adjacent to NM and NL in chicks from 7 days of incubation to 12 days posthatch. Immunocytochemical techniques revealed the presence of approximately 150 GABA-labeled neurons within the neuropil surrounding NM and NL on each side of the brainstem. Most of these neurons are located between NM and NL and along the lateral border of NM. GABAergic neurons are multipolar; their thick dendritic processes branch extensively and give rise to several thin, secondary processes. Frequently, the GABA-labeled processes arborize within NM or NL. The morphology of these non-NM/NL neurons was investigated further with Golgi impregnation and specific neuronal markers (antisera to microtubule-associated protein). Our observations suggest that a considerable portion of GABAergic input to NM and NL originates from local GABAergic neurons. In order to determine other possible sources of GAB...Continue Reading

References

Feb 1, 1978·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·M M Mesulam
Mar 8, 1989·The Journal of Comparative Neurology·J S Deitch, E W Rubel
Mar 8, 1989·The Journal of Comparative Neurology·J S Deitch, E W Rubel
Jun 15, 1989·Hearing Research·R A Code, E W Rubel
Aug 8, 1989·The Journal of Comparative Neurology·C E CarrM Konishi
Jan 1, 1986·Annals of the New York Academy of Sciences·L I BinderL I Rebhun
Aug 13, 1986·Brain Research·R J WentholdR A Altschuler
Apr 8, 1987·The Journal of Comparative Neurology·R C Roberts, C E Ribak
May 15, 1987·The Journal of Comparative Neurology·K M SpanglerW B Warr
Jun 8, 1987·The Journal of Comparative Neurology·J K Moore, R Y Moore
Feb 1, 1969·The Journal of Comparative Neurology·R D Lund
Apr 1, 1981·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·S M HsuH Fanger
Apr 10, 1983·The Journal of Comparative Neurology·J C Adams
Feb 10, 1983·The Journal of Comparative Neurology·T N ParksJ W Conlee
Jun 1, 1981·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·J C Adams
Jan 1, 1981·Neuroscience·M C Whitehead, D K Morest
Mar 1, 1980·The Journal of Comparative Neurology·B Chronwall, J R Wolff

❮ Previous
Next ❯

Citations

Apr 28, 2004·Hearing Research·Ye-Zhong Tang, C E Carr
Apr 29, 1998·Brain Research. Developmental Brain Research·R A Code, A E McDaniel
Feb 15, 2001·Journal of Chemical Neuroanatomy·Y AtojiY Suzuki
Nov 21, 1998·The European Journal of Neuroscience·S Brückner, R L Hyson
Apr 29, 2011·Journal of Neurophysiology·R Michael BurgerEdwin W Rubel
Jul 31, 2009·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Sidney P KuoLaurence O Trussell
Apr 22, 2011·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Zheng-Quan TangYong Lu
Apr 10, 1995·The Journal of Comparative Neurology·C K Henkel, J K Brunso-Bechtold
Nov 22, 1990·The Journal of Comparative Neurology·R A CodeE W Rubel
Nov 8, 1991·The Journal of Comparative Neurology·C K Henkel, J K Brunso-Bechtold
Oct 15, 1994·The Journal of Comparative Neurology·E A LachicaE W Rubel
May 1, 2007·Journal of Chemical Neuroanatomy·Raphael Pinaud, Claudio V Mello
Jun 25, 2005·The Journal of Comparative Neurology·R Michael BurgerEdwin W Rubel
Feb 3, 2004·The Journal of Comparative Neurology·Yong LuEdwin W Rubel
Jul 1, 2010·The Journal of Comparative Neurology·Kai YanCatherine E Carr
May 23, 2014·Frontiers in Neural Circuits·Harunori Ohmori
Dec 16, 2000·The Journal of Comparative Neurology·D Soares, C E Carr
Jul 2, 2002·Journal of Neurophysiology·Daphne SoaresCatherine E Carr

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.